Prevention of occlusal caries using Vanish^TM XT: an 18-month follow-up randomized clinical trial.

IF 2.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE BMC Oral Health Pub Date : 2024-11-01 DOI:10.1186/s12903-024-05095-8

Alaa Baik, Najlaa Alamoudi, Osama Felemban, Azza El-Housseiny, Eman Almabadi, Khadijah Baik, Amani Altuwirqi, Ibrahim Masoud

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Abstract

Aim: To evaluate the effectiveness of a light curable resin-modified glass ionomer varnish (Vanish^TM XT) in the prevention of occlusal caries compared to topical fluoride varnish in newly erupted first permanent molars over 18 months.

Methods: A randomized controlled clinical trial was conducted using a split-mouth design. A total of 53 participants aged 6-9 years with 97 pairs of caries-free newly erupted first permanent molars were enrolled in the study. Each molar in the pair was randomly assigned either to the experimental group, which received the Vanish^TM XT Extended Contact Varnish, or to the control group, which received topical fluoride varnish (Vanish^TM 5% Sodium Fluoride White Varnish). Follow-ups were performed at 6, 12, and 18 months to evaluate dental caries development.

Results: At the 6-month follow-up, caries development was significantly higher in the control group (7.8%) than that in the experimental group (0%) (P = 0.031). At the 12-month follow-up, significantly (P = 0.012) more occlusal caries developed in the control group (12.2%) compared to the experimental group (1.2%). At the 18-month follow-up, significantly (P = 0.002) more occlusal caries developed in the control group (14.3%) compared to the experimental group (1.1%).

Conclusion: Compared to fluoride varnish, Vanish^TM XT was significantly more effective in preventing caries on the occlusal surfaces of newly erupted first permanent molars at 6, 12, and 18 months.

Trial registration: Registration number at ClinicalTrials.gov: NCT04579536 on 08/10/ 2020, retrospectively registered.

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使用 VanishTM XT 预防咬合面龋齿：一项为期 18 个月的随访随机临床试验。

目的：评估光固化树脂改性玻璃离子膜清漆（VanishTM XT）与局部氟化物清漆相比，在 18 个月内对新萌出第一恒磨牙的咬合龋预防效果：采用分口设计进行了随机对照临床试验。共有 53 名年龄在 6-9 岁、97 对新萌出第一恒磨牙没有龋齿的参与者参加了这项研究。这对臼齿中的每颗臼齿都被随机分配到实验组和对照组，实验组接受的是 VanishTM XT 长效接触型清漆，对照组接受的是局部氟化物清漆（VanishTM 5%氟化钠白色清漆）。在 6 个月、12 个月和 18 个月时进行随访，以评估龋齿的发展情况：结果：在 6 个月的随访中，对照组的龋齿发生率（7.8%）明显高于实验组（0%）（P = 0.031）。在 12 个月的随访中，对照组的咬合龋发生率（12.2%）明显高于实验组（1.2%）（P = 0.012）。在 18 个月的随访中，对照组（14.3%）的咬合龋发生率明显高于实验组（1.1%）（P = 0.002）：结论：与氟化物清漆相比，VanishTM XT在6、12和18个月时预防新萌出第一恒磨牙咬合面龋齿的效果明显更好：试验注册：ClinicalTrials.gov 上的注册号：试验注册：ClinicalTrials.gov 注册号：NCT04579536，2020 年 10 月 8 日，回顾性注册。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Oral Health DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

6.90%

发文量

481

审稿时长

6-12 weeks

期刊介绍： BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.