An International Delphi Consensus on the Management of Pollen-Food-Allergy Syndrome: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee.

Taha Al-Shaikhly, Amanda Cox, Anna Nowak-Wegrzyn, Antonella Cianferoni, Constance Katelaris, Didier G Ebo, George N Konstantinou, Hannelore Brucker, Hyeon-Jong Yang, Jennifer L P Protudjer, José Laerte Boechat, Joyce E Yu, Julie Wang, Karen S Hsu Blatman, Lukasz Blazowski, Mahesh Padukudru Anand, Manish Ramesh, Maria J Torres, Mark Holbreich, Richard Goodman, Richard L Wasserman, Russell Hopp, Sakura Sato, Isabel Skypala
{"title":"An International Delphi Consensus on the Management of Pollen-Food-Allergy Syndrome: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee.","authors":"Taha Al-Shaikhly, Amanda Cox, Anna Nowak-Wegrzyn, Antonella Cianferoni, Constance Katelaris, Didier G Ebo, George N Konstantinou, Hannelore Brucker, Hyeon-Jong Yang, Jennifer L P Protudjer, José Laerte Boechat, Joyce E Yu, Julie Wang, Karen S Hsu Blatman, Lukasz Blazowski, Mahesh Padukudru Anand, Manish Ramesh, Maria J Torres, Mark Holbreich, Richard Goodman, Richard L Wasserman, Russell Hopp, Sakura Sato, Isabel Skypala","doi":"10.1016/j.jaip.2024.09.037","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Pollen-food-allergy syndrome (PFAS) is common among patients with allergic rhinitis. Treatment recommendations for patients with PFAS remain variable.</p><p><strong>Objective: </strong>To develop consensus recommendation statements for managing patients with PFAS.</p><p><strong>Methods: </strong>An international panel of allergists, researchers, and nutritionists with an interest in PFAS from 25 different institutions across 11 countries convened and a list of statements was written by 3 authors. The RAND/University of California Los Angeles methodology was adopted to establish consensus on the statements.</p><p><strong>Results: </strong>After 2 Delphi rounds, a consensus was reached on 14 statements. The panel agreed that patients with PFAS would benefit from counseling on the nature and basis of PFAS and the rare chance of more severe systemic reactions and their recognition. The panel agreed on avoiding the raw food responsible for the index reaction, but not potentially cross-reactive fruits/vegetables based on the responsible food of the index reaction. Epinephrine autoinjectors should be recommended for patients with PFAS who experienced severe symptoms (beyond the oropharynx) or for patients considered at risk for severe reactions. The panel agreed that the benefit of allergen immunotherapy remains unclear and that PFAS should not be considered the primary indication for such intervention.</p><p><strong>Conclusions: </strong>We developed consensus statements regarding counselling patients about the nature and severity of PFAS, potential risk factors, dietary avoidance, epinephrine autoinjector prescription, and allergen immunotherapy consideration for patients with PFAS.</p>","PeriodicalId":51323,"journal":{"name":"Journal of Allergy and Clinical Immunology-In Practice","volume":null,"pages":null},"PeriodicalIF":8.2000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Allergy and Clinical Immunology-In Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jaip.2024.09.037","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Pollen-food-allergy syndrome (PFAS) is common among patients with allergic rhinitis. Treatment recommendations for patients with PFAS remain variable.

Objective: To develop consensus recommendation statements for managing patients with PFAS.

Methods: An international panel of allergists, researchers, and nutritionists with an interest in PFAS from 25 different institutions across 11 countries convened and a list of statements was written by 3 authors. The RAND/University of California Los Angeles methodology was adopted to establish consensus on the statements.

Results: After 2 Delphi rounds, a consensus was reached on 14 statements. The panel agreed that patients with PFAS would benefit from counseling on the nature and basis of PFAS and the rare chance of more severe systemic reactions and their recognition. The panel agreed on avoiding the raw food responsible for the index reaction, but not potentially cross-reactive fruits/vegetables based on the responsible food of the index reaction. Epinephrine autoinjectors should be recommended for patients with PFAS who experienced severe symptoms (beyond the oropharynx) or for patients considered at risk for severe reactions. The panel agreed that the benefit of allergen immunotherapy remains unclear and that PFAS should not be considered the primary indication for such intervention.

Conclusions: We developed consensus statements regarding counselling patients about the nature and severity of PFAS, potential risk factors, dietary avoidance, epinephrine autoinjector prescription, and allergen immunotherapy consideration for patients with PFAS.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
关于花粉-食物过敏综合征管理的国际德尔菲共识:AAAAI食品不良反应委员会工作组报告。
背景:花粉-食物过敏综合征(PFAS)在过敏性鼻炎患者中很常见。针对 PFAS 患者的治疗建议仍不尽相同:目的:制定治疗 PFAS 患者的共识建议声明:方法:由来自 11 个国家 25 个不同机构、对全氟辛烷磺酸感兴趣的过敏症专家、研究人员和营养学家组成的国际小组召开会议,并由 3 位作者撰写了一份声明清单。采用兰德公司/加州大学洛杉矶分校的方法就声明达成共识:结果:经过两轮德尔菲讨论,就 14 项声明达成了共识。专家小组一致认为,就全氟辛烷磺酸的性质和基础、发生更严重全身反应的罕见几率及其识别提供咨询,将使全氟辛烷磺酸患者受益。专家小组同意避免食用导致指标反应的生食,但不包括可能产生交叉反应的水果/蔬菜。对于出现严重症状(口咽部以外)的 PFAS 患者或被认为有可能出现严重反应的患者,应推荐使用肾上腺素自动注射器。专家组一致认为,过敏原免疫疗法的益处尚不明确,PFAS 不应被视为此类干预措施的主要适应症:我们就向患者提供有关 PFAS 的性质和严重程度、潜在风险因素、饮食避免、肾上腺素自动注射器处方以及考虑对 PFAS 患者进行过敏原免疫治疗等方面的咨询达成了共识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
11.10
自引率
9.60%
发文量
683
审稿时长
50 days
期刊介绍: JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.
期刊最新文献
Guidance for the Evaluation by Payors of Claims Submitted Using Current Procedural Terminology Codes 95165, 95115, and 95117. Bee/Vespula venom-specific IgE ratio ≥5:1 indicates culprit insect in double-sensitized patients. Class I HLA Alleles are associated with an increased risk of osimertinib-induced hypersensitivity. AAAAI Position Statement on Changing Electronic Health Record Allergy Documentation to "Alerts" to Lead to Easily Understood, Actionable Labels. An International Delphi Consensus on the Management of Pollen-Food-Allergy Syndrome: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1