Mortality for Alzheimer's disease during the COVID-19 pandemic.

IF 3.5 3区医学 Q2 GERIATRICS & GERONTOLOGY European Geriatric Medicine Pub Date : 2024-11-01 DOI:10.1007/s41999-024-01096-6

Camilla Mattiuzzi, Giuseppe Lippi

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Abstract

Aim: Coronavirus disease 2019 (COVID-19) negatively impacts the progression of Alzheimer's disease. The aim of this study was to determine whether mortality from Alzheimer's disease has changed during the COVID-19 pandemic.

Methods: We searched the WONDER database, to obtain cumulative and sex-specific age-adjusted death rates of Alzheimer's disease between the years 2018 and 2022.

Results: Cumulative age-adjusted mortality rate displayed a peak in 2020, followed by gradual decline thereafter. The data for both sexes mirror that of total population, peaking in 2020, followed by a decline thereafter. The relative increase in age-adjusted mortality for Alzheimer's disease in 2020 compared to 2019 was + 8.7% in the total population, + 6.1% in men and + 10.1% in women.

Conclusions: Frail people, such as those with Alzheimer's disease, may be more vulnerable to the risk of dying during an outbreak of infectious disease, paving the way for increased preventive and protective measures in the unfortunate event of the next pandemic.

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COVID-19 大流行期间阿尔茨海默病的死亡率。

目的：2019 年冠状病毒病（COVID-19）会对阿尔茨海默病的进展产生负面影响。本研究旨在确定阿尔茨海默病死亡率在 COVID-19 大流行期间是否发生了变化：我们检索了 WONDER 数据库，以获得 2018 年至 2022 年间阿尔茨海默病的累计和特定性别年龄调整后死亡率：经年龄调整后的累计死亡率在 2020 年达到峰值，之后逐渐下降。男女两性的数据与总人口的数据相同，在 2020 年达到峰值，之后逐渐下降。与 2019 年相比，2020 年阿尔茨海默病年龄调整后死亡率的相对增幅为：总人口 + 8.7%，男性 + 6.1%，女性 + 10.1%：体弱者，如阿尔茨海默氏症患者，在传染病爆发时可能更容易面临死亡风险，这为在下一次大流行病不幸发生时加强预防和保护措施铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Geriatric Medicine GERIATRICS & GERONTOLOGY-

CiteScore

6.70

自引率

2.60%

发文量

114

审稿时长

6-12 weeks

期刊介绍： European Geriatric Medicine is the official journal of the European Geriatric Medicine Society (EUGMS). Launched in 2010, this journal aims to publish the highest quality material, both scientific and clinical, on all aspects of Geriatric Medicine. The EUGMS is interested in the promotion of Geriatric Medicine in any setting (acute or subacute care, rehabilitation, nursing homes, primary care, fall clinics, ambulatory assessment, dementia clinics..), and also in functionality in old age, comprehensive geriatric assessment, geriatric syndromes, geriatric education, old age psychiatry, models of geriatric care in health services, and quality assurance.