Quality of food intake and spontaneous clearance of Human papillomavirus in women.

Abstract

Background: Human papillomavirus is known to be the main cause of cervical cancer. Given that cervical cancer is still one of the leading causes of death in women of reproductive age, it is very important to prevent HPV infection and its persistence.

Objective: The aim of our study was to explore the quality of the diet in the spontaneous clearance of cervical HPV infection and its persistence. Furthermore, we have assessed the associations of overall diet quality and dietary components with HPV occurrence and clinical resolution of HPV over time.

Methods: 200 women of age between 20 and 68 years were included in this prospective study. Patients were tested for the presence of HPV subtypes, and were given questionnaires about their dietary habits.

Results: 43 patients were positive for HPV virus, and 157 patients were negative. Among the positive HPV patients, the mean value (±SEM) of the score was 12.88±0.6822 (min=7, max=21) with upper CI of mean 14.26 and coefficient of variation of 34.72%.

Conclusion: Various antioxidants have different abilities to influence the course of HPV-mediated cervical cancer. This study showed that women who did not consume fruits, and dark-green vegetables had a higher risk of HPV infection (Tab. 2, Fig. 3, Ref. 40): Text in PDF www.elis.sk Keywords: cervical cancer, human papillomavirus, folate, vitamin D3, dietary intake.