Determinants of residual dizziness in benign positional paroxysmal vertigo patients after effective repositioning manoeuvres: the mediating role of blood lipid levels in a single-centre analysis.

IF 0.8 4区 医学 Q3 OTORHINOLARYNGOLOGY Journal of Laryngology and Otology Pub Date : 2024-11-04 DOI:10.1017/S0022215124001798
Guanyu Wang
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Abstract

Objectives: The aim of this study is to identify risk factors for residual dizziness in benign paroxysmal positional vertigo patients after repositioning manoeuvres and explore the mediation role of lipid indicators.

Methodology: In all, 110 benign paroxysmal positional vertigo patients treated from January 2019 to February 2022 were studied. Data on demographics, diseases, behaviours, and lipids were collected. Multivariate logistic regression assessed risk factors, and mediation analyses explored effects via lipid indicators. Odds ratios and 95 per cent confidence intervals are reported.

Results: Differences between groups with and without residual dizziness included limb weakness, hypertension, nausea, arteriosclerosis, medication, dizziness handicap inventory scores, hospital anxiety and depression scale scores, and lipid distributions (p < 0.05). Significant risk factors were sleep disorders, medication, hypertension, triglycerides, and total cholesterol (p < 0.05). Total cholesterol mediated 9.1 per cent of the effect of sleep disorders on residual dizziness.

Conclusion: Managing lipid levels and sleep disorders is crucial in treating residual dizziness in benign paroxysmal positional vertigo patients after repositioning.

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BPPV患者在有效复位操作后残留头晕的决定因素:单中心分析中血脂水平的中介作用
目的:本研究旨在探讨良性阵发性体位性眩晕患者复位后残留头晕的危险因素,并探讨脂质指标的中介作用。方法:选取2019年1月至2022年2月治疗的110例良性阵发性体位性眩晕患者作为研究对象。收集了人口统计、疾病、行为和血脂方面的数据。多因素logistic回归评估危险因素,并通过脂质指标进行中介分析。报告了比值比和95%的置信区间。结果:残馀头晕组与无残馀头晕组在肢体无力、高血压、恶心、动脉硬化、用药、头晕障碍量表评分、医院焦虑抑郁量表评分、血脂分布等方面的差异均有统计学意义(p < 0.05)。睡眠障碍、药物、高血压、甘油三酯和总胆固醇是显著危险因素(p < 0.05)。总胆固醇介导了9.1%的睡眠障碍对残余头晕的影响。结论:控制脂质水平和睡眠障碍是治疗良性阵发性体位性眩晕患者复位后残留头晕的关键。
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来源期刊
Journal of Laryngology and Otology
Journal of Laryngology and Otology 医学-耳鼻喉科学
CiteScore
3.20
自引率
11.80%
发文量
593
审稿时长
3-6 weeks
期刊介绍: The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.
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