Pathological Mechanism and Clinical Therapy Progress of Schlemm's Canal.

IF 1.8 4区 医学 Q3 OPHTHALMOLOGY Journal of Ophthalmology Pub Date : 2024-10-26 eCollection Date: 2024-01-01 DOI:10.1155/2024/9978312
Yasha Zhou, Zhenxin Liu, Wenyong Gao, Yijing Yang, Qinghua Peng, Hanyu Tan
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Abstract

Schlemm's canal (SC) is a small circular canal in the deep part of the sclera at the junction of the sclera and cornea. As an integral component of the aqueous humor outflow, its structure and function are essential in regulating intraocular pressure (IOP). If SC develops lesions, the drainage of aqueous humor would be obstructed, leading to increased intraocular pressure and injury to the optic nerve. With the rapid development of minimally invasive glaucoma surgery, an increasing number of surgeons became familiar with SC, and the area generated substantial academic attention. The pathological mechanism and the therapy for SC that had been studied in recent years are summarized in this article, hoping to provide ideas for the treatment of glaucoma in the future.

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施莱姆氏管的病理机制和临床治疗进展。
施莱姆管(Schlemm's canal,SC)是位于巩膜深部、巩膜和角膜交界处的一个圆形小管。作为房水外流的重要组成部分,其结构和功能对调节眼压(IOP)至关重要。如果 SC 发生病变,房水的排泄就会受阻,导致眼压升高和视神经损伤。随着微创青光眼手术的迅速发展,越来越多的外科医生开始熟悉 SC,该领域也引起了学术界的广泛关注。本文对近年来研究的SC的病理机制和治疗方法进行了总结,希望能为今后青光眼的治疗提供思路。
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来源期刊
Journal of Ophthalmology
Journal of Ophthalmology MEDICINE, RESEARCH & EXPERIMENTAL-OPHTHALMOLOGY
CiteScore
4.30
自引率
5.30%
发文量
194
审稿时长
6-12 weeks
期刊介绍: Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.
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