Spindle Cell Neoplasms Unique to the Sinonasal Tract

Q1 Medicine Surgical Pathology Clinics Pub Date : 2024-09-02 DOI:10.1016/j.path.2024.07.009

Alex N. Perez MD , Carlos N. Prieto Granada MD

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鼻窦道特有的纺锤形细胞肿瘤

纺锤形细胞肿瘤包括窦道血管纤维瘤（STA）、窦道腺细胞瘤（GPC）和窦道双型肉瘤（BSNS）。这些实体具有一些共同的临床、组织形态学、免疫组化甚至分子特征。然而，每种肿瘤类型都有其独特的特征。STA 表现为严重的胶原化和血管基质，明显与潜在的激素变化有关。GPC 始终表现出单形、卵圆形的细胞学外观，IHC 显示其始终存在 Beta 连环素核聚集的特征。最后，BSNS 是一种平淡无奇的神经样肿瘤，其特点是 S100 和平滑肌标记物持续共表达，特定的基因重排是这一实体的独特特征。

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来源期刊

Surgical Pathology Clinics Medicine-Surgery

CiteScore

4.40

自引率

0.00%

发文量

期刊介绍： This newest addition to the Clinics Series keeps you current on the information that is essential to every practicing surgical pathologist, from the latest techniques and approaches to detailed discussions on differential diagnosis. It devotes each and every issue exclusively to surgical pathology and its associated problems and is enhanced by abundant full-color images. Each issue focuses on a single topic-and is overseen by Guest Editors who are experts in their field-providing information of practical value on service while also offering material that increases understanding.

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