[White lesions of the buccal mucosa: think outside the box, too].

E F A Dagal, K Delli, A I Fatta, B van der Vegt, G F H Diercks, A Vissink, J M Alberga
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Abstract

A healthy, 49-year-old healthy woman presented at a maxillofacial surgery department with pain and a burning sensations in the mouth. She had experienced the discomfort for a year and it had made eating difficult. Clinical examination revealed white, plaque-like lesions on the buccal mucosa and tongue that could not be scraped off. A biopsy was taken by another health professional and oral lichen planus was diagnosed; treatment with triamcinolone dental paste and later clobetasol mouthwash followed. Neither treatment was sufficiently effective. A new biopsy confirmed a diagnosis of oral lichen sclerosus. Lichen sclerosus is a mucocutaneous condition commonly affecting the anogenital region, while the oral variant presents as white plaque. The differential diagnoses consisted of oral lichen planus, oral manifestations of systemic sclerosus (scleroderma) and leukoplakia. When other kinds of corticosteroid therapy are insufficiently effective, an intralesional injection of triamcinolone acetonide might be considered, which proved to be effective in this case.

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[口腔黏膜白色病变:也要跳出思维定式]。
一名 49 岁的健康女性因口腔疼痛和烧灼感来到颌面外科就诊。这种不适感已经持续了一年,导致进食困难。临床检查发现,她的口腔黏膜和舌头上有白色斑块状病变,无法刮除。另一名医护人员对其进行了活检,确诊为口腔扁平苔藓;随后使用曲安奈德牙膏和氯倍他索漱口水进行治疗。这两种治疗方法的效果都不理想。新的活组织检查确诊为口腔硬皮病。硬皮病是一种粘膜皮肤病,常见于肛门生殖器部位,而口腔变种表现为白色斑块。鉴别诊断包括口腔扁平苔藓、全身性硬皮病(硬皮病)的口腔表现和白斑病。当其他类型的皮质类固醇治疗效果不佳时,可以考虑在局部注射曲安奈德丙酮,这在本病例中被证明是有效的。
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