Percutaneous aspiration for shortening time to blood cultures sterilization in right-sided infective endocarditis and vegetations.

IF 3.8 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Clinical Research in Cardiology Pub Date : 2024-11-06 DOI:10.1007/s00392-024-02567-3

Francisco Polo Tirado, Asaad Nakhle, Eric Gnall, Zach Rozenbaum

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Abstract

Background: Surgical intervention is associated with earlier clearance of bacteremia in infective endocarditis (IE).

Aim: We hypothesized that vegetectomies using percutaneous aspiration shortens time to sterilization of blood cultures in patients with right-sided IE and vegetations.

Results: The cohort included 37 patients, 23 treated conservatively, and 14 underwent percutaneous vegetectomy. The median time to blood culture sterilization among patients with bacteremia over 7 days was 16.5 (IQR 9.75-29) for patients treated conservatively and 11.5 (IQR 8.5-11.5) for those who underwent vegetectomy. The two patients who required mechanical ventilation were among the vegetectomy group, and the single patient who died during the same admission was treated conservatively. There were no complications in the vegetectomy group.

Conclusion: These data are hypothesis-generating, suggesting that utilizing percutaneous aspiration in patients with right-sided IE and vegetations shortens time to sterilization of blood cultures, and possibly improves outcomes.

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经皮穿刺抽吸缩短右侧感染性心内膜炎和植皮的血液培养物消毒时间。

背景：目的：我们假设经皮穿刺植物切除术可缩短右侧感染性心内膜炎（IE）和植物栓塞患者血液培养的灭菌时间：结果：37 名患者中，23 人接受了保守治疗，14 人接受了经皮植物切除术。保守治疗的患者中，7 天以上菌血症患者血液培养物灭菌的中位时间为 16.5（IQR 9.75-29）天，植物切除术患者血液培养物灭菌的中位时间为 11.5（IQR 8.5-11.5）天。植物切除组中有两名患者需要机械通气，而在同一次入院过程中死亡的一名患者则接受了保守治疗。植物切除组没有出现并发症：这些数据具有假设性，表明对右侧 IE 和植物瘤患者采用经皮穿刺抽吸可缩短血液培养的灭菌时间，并可能改善预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Research in Cardiology 医学-心血管系统

CiteScore

11.40

自引率

4.00%

发文量

140

审稿时长

4-8 weeks

期刊介绍： Clinical Research in Cardiology is an international journal for clinical cardiovascular research. It provides a forum for original and review articles as well as critical perspective articles. Articles are only accepted if they meet stringent scientific standards and have undergone peer review. The journal regularly receives articles from the field of clinical cardiology, angiology, as well as heart and vascular surgery. As the official journal of the German Cardiac Society, it gives a current and competent survey on the diagnosis and therapy of heart and vascular diseases.