Clonal distribution and molecular characterization of Staphylococcus aureus isolated strains in Chania and Heraklion, Crete.

Q2 Medicine Medicine and Pharmacy Reports Pub Date : 2024-10-01 Epub Date: 2024-10-30 DOI:10.15386/mpr-2783
Eftychios Vittorakis, Mihaela Laura Vica, Stanca-Lucia Pandrea, Amanda Rădulescu, Calina Oana Zervaki, Evangelos Vittorakis, Sofia Maraki, Viktoria Eirini Mavromanolaki, Michael Ewald Schürger, Vlad Sever Neculicioiu, Evangelia Papadomanolaki, Lia Monica Junie
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Abstract

Aim: This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of Staphylococcus aureus infections.

Methods: The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.

Results: The highest infection prevalence observed in the older adults (≥65 years) age group. The predominant infection types were skin lesions (39.72) and respiratory tract infection (22.7%). Antibiotic resistance testing revealed that 57.44% of strains were MRSA, with high resistance to Tetracycline, Ciprofloxacin, Kanamycine Erythromycin and Clindamycin. Molecular analysis showed 19.14% of strains were Pvl-positive, highlighting the presence of both MRSA and MSSA strains with Pvl genes.

Conclusions: The study underscores the need for continuous surveillance and targeted infection control strategies to manage the spread of MRSA, particularly in vulnerable populations.

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克里特岛夏尼亚和伊拉克利翁金黄色葡萄球菌分离菌株的克隆分布和分子特征。
目的:本研究调查了金黄色葡萄球菌感染的人口分布、抗生素耐药性概况和分子特征:研究对象是来自克里特岛夏尼亚和伊拉克利翁的 141 名患者,其中 60.4% 为男性:结果:老年人(≥65 岁)的感染率最高。主要感染类型为皮肤损伤(39.72%)和呼吸道感染(22.7%)。抗生素耐药性检测显示,57.44%的菌株为 MRSA,对四环素、环丙沙星、卡那霉素、红霉素和克林霉素的耐药性较高。分子分析显示 19.14% 的菌株 Pvl 阳性,这表明 MRSA 和 MSSA 菌株中都存在 Pvl 基因:这项研究强调了持续监测和有针对性的感染控制策略的必要性,以控制 MRSA 的传播,尤其是在易感人群中的传播。
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来源期刊
Medicine and Pharmacy Reports
Medicine and Pharmacy Reports Medicine-Medicine (all)
CiteScore
3.10
自引率
0.00%
发文量
63
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