Squamous cell carcinoma arising from anal fistula in an HIV-positive individual: a case report.

IF 0.4 Q4 SURGERY Journal of Surgical Case Reports Pub Date : 2024-11-05 eCollection Date: 2024-11-01 DOI:10.1093/jscr/rjae686
Jie Yang, Liman Zhang, Qiang Wang, Lili Wang
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Abstract

Chronic anal fistula represents a prevalent form of perianal disease that frequently originates from perianal infection. Specifically, perianal abscesses that are inadequately or improperly treated are susceptible to the development of chronic anal fistulas. In HIV-infected individuals, an impaired immune system significantly diminishes the body's capacity to combat infections and inflammation, thereby complicating the healing process of anal fistulas. Moreover, the impact of HIV on tissue repair results in a markedly prolonged healing process for wounds and tissue damage in these patients, exacerbating the difficulty in anal fistula resolution. Chronic anal fistulas that remain untreated for extended periods not only severely impair the patient's quality of life but also pose an increased risk of malignant transformation.

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一名艾滋病毒呈阳性者肛瘘引发的鳞状细胞癌:病例报告。
慢性肛瘘是一种常见的肛周疾病,通常源于肛周感染。具体来说,肛周脓肿治疗不充分或不当很容易发展成慢性肛瘘。艾滋病毒感染者的免疫系统受损,大大降低了机体对抗感染和炎症的能力,从而使肛瘘的愈合过程变得更加复杂。此外,艾滋病毒对组织修复的影响导致这些患者伤口和组织损伤的愈合过程明显延长,从而加剧了肛瘘治愈的难度。长期得不到治疗的慢性肛瘘不仅会严重影响患者的生活质量,还会增加恶变的风险。
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
559
审稿时长
11 weeks
期刊最新文献
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