Navigating the Diagnostic Challenges in Lymph Node Cytology: The Case of Reactive Hyperplasia.

IF 1.2 4区 医学 Q4 CELL BIOLOGY Cytopathology Pub Date : 2024-11-05 DOI:10.1111/cyt.13455
Elena Vigliar, Gennaro Acanfora, Mauro Buono, Claudio Bellevicine, Marco Picardi, Giancarlo Troncone
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Abstract

Fine needle cytology (FNC) is a pivotal diagnostic tool for distinguishing between benign and malignant lymphadenopathies mainly because of its minimal invasiveness, cost-effectiveness and accuracy. A major requirement for maximising diagnostic accuracy is proper sample management of aspirated cellular material. In this diagnostic process, the morphological evaluation of adequate smears is paramount, guiding cytopathologists in the selection of appropriate ancillary tests through the recognition of cell size and patterns of distribution. Here, we describe a peculiar 'concentric ovals distribution pattern', frequently observed in the FNC of benign reactive lymph nodes, which may represent an aid in the cytological diagnosis of reactive hyperplasia.

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驾驭淋巴结细胞学诊断难题:反应性增生病例。
细针细胞学(FNC)是区分良性和恶性淋巴腺疾病的重要诊断工具,这主要是因为它具有微创、成本效益高和准确性高等特点。最大限度提高诊断准确性的一个主要要求是对抽吸的细胞材料进行适当的样本管理。在这一诊断过程中,充分涂片的形态学评估至关重要,它通过识别细胞大小和分布模式,指导细胞病理学家选择适当的辅助检查。在这里,我们描述了一种在良性反应性淋巴结的 FNC 中经常观察到的奇特的 "同心椭圆分布模式",它可能有助于反应性增生的细胞学诊断。
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来源期刊
Cytopathology
Cytopathology 生物-病理学
CiteScore
2.30
自引率
15.40%
发文量
107
审稿时长
6-12 weeks
期刊介绍: The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.
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