Ossifying Panniculitis Presenting as a Painful Nodule on the Abdomen.

IF 1.1 4区 医学 Q4 DERMATOLOGY American Journal of Dermatopathology Pub Date : 2024-11-05 DOI:10.1097/DAD.0000000000002884
Rosemary Oaks, Abigail Beard, Richard Miller, Keith Baribault
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Abstract

Abstract: Myositis ossificans is a benign ossifying nodule that can affect any type of tissue but is most commonly found in muscle. Occurrence in the soft tissue of the subcutis is less common and has been referred to as panniculitis ossificans. In this case report, we describe a 46-year-old woman who presented with a 1.7 × 2.0 cm lesion on the abdomen that had been present for several months, was painful, and easily irritated by clothing. Initial clinical assessment based on history and physical examination was an epidermal cyst and removal by excision was performed. Initial histologic findings showed a spindle cell proliferation in the subcutis along with bone formation. Osteoblasts were noted to be rimming the bone and giant cells were present. The spindle cells were SMA positive and partially factor XIIIa positive while S100 protein staining was negative, confirming the diagnosis of panniculitis ossificans.

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以腹部疼痛性结节为表现的骨化性盘膜炎
摘要:骨化性肌炎是一种良性骨化性结节,可影响任何类型的组织,但最常见于肌肉。发生在皮下软组织的情况较少见,被称为 "骨化性浆膜炎"。在本病例报告中,我们描述了一名 46 岁女性的病例,她的腹部有一个 1.7 × 2.0 厘米的病变,已存在数月之久,疼痛难忍,而且很容易受到衣物的刺激。根据病史和体格检查,初步临床评估为表皮囊肿,并进行了切除术。初步组织学检查结果显示,皮下有纺锤形细胞增生,并伴有骨形成。骨骼边缘可见成骨细胞和巨细胞。纺锤形细胞 SMA 阳性,部分因子 XIIIa 阳性,而 S100 蛋白染色阴性,确诊为骨化性泛发炎。
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来源期刊
CiteScore
1.80
自引率
9.10%
发文量
453
审稿时长
3 months
期刊介绍: The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports. With the The American Journal of Dermatopathology you''ll be able to: -Incorporate step-by-step coverage of new or difficult-to-diagnose conditions from their earliest histopathologic signs to confirmatory immunohistochemical and molecular studies. -Apply the latest basic science findings and clinical approaches to your work right away. -Tap into the skills and expertise of your peers and colleagues the world over peer-reviewed original articles, "Extraordinary cases reports", coverage of practical guidelines, and graphic presentations. -Expand your horizons through the Journal''s idea-generating forum for debating controversial issues and learning from preeminent researchers and clinicians
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