Radiation Therapy for the Treatment of Osteoarthritis.

IF 3.4 3区 医学 Q2 ONCOLOGY Practical Radiation Oncology Pub Date : 2024-11-05 DOI:10.1016/j.prro.2024.09.003
James B Yu, David J Grew, Matthew B Spraker, Jason M Beckta, Chirag Shah, Jeffrey V Brower
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Abstract

Osteoarthritis is a common cause of pain and disability in the United States. Many patients experience pain that is refractory or unable to be treated by traditional treatments such as exercise, physical therapy, nonsteroidal anti-inflammatory drugs, and/or cyclooxygenase-2 inhibitors. For patients with medically refractory disease, intra-articular corticosteroid therapy, hyaluronic acid, or surgery can be considered. However, for many older patients with significant impairment in quality of life related to osteoarthritis, radiation therapy is a noninvasive treatment option that has a long history of global use. In this topic discussion, we review the clinical evidence supporting treatment of osteoarthritis, as well as considerations for how to select which patient and joint to treat. We discuss technical considerations for treatment including dose and immobilization, assessment of treatment response, and the role of retreatment.

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治疗骨关节炎的放射疗法。
在美国,骨关节炎是导致疼痛和残疾的常见原因。许多患者的疼痛难治,或无法通过运动、理疗、非甾体抗炎药和/或环氧合酶-2 抑制剂等传统疗法治疗。对于药物难治性疾病患者,可以考虑关节内皮质类固醇治疗、透明质酸或手术治疗。然而,对于许多因骨关节炎导致生活质量明显下降的老年患者来说,放射治疗是一种非侵入性治疗方法,在全球使用的历史悠久。在本专题讨论中,我们将回顾支持骨关节炎治疗的临床证据,以及如何选择治疗患者和关节的注意事项。我们将讨论治疗的技术注意事项,包括剂量和固定、治疗反应评估以及再治疗的作用。
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来源期刊
Practical Radiation Oncology
Practical Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
5.20
自引率
6.10%
发文量
177
审稿时长
34 days
期刊介绍: The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes: Original articles focusing on patient safety, quality measurement, or quality improvement initiatives Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues ASTRO guidelines, position papers, and consensus statements Essays that highlight enriching personal experiences in caring for cancer patients and their families.
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