Suhmi Hwang, Phil M. Preuß, Wilm Pickhardt, Sven Grätz and Lars Borchardt
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引用次数: 0
Abstract
A cyanation reaction was performed inside a ball mill system utilizing catalytically active milling balls, while avoiding the use of solvents and ligands. Additionally, replacing the highly toxic cyanide source with potassium hexacyanoferrate(II) leads to a safer reaction environment. Yields of up to 90% were achieved in as little as 4 hours at room temperature. The oxidative addition and transmetalation step could be observed via X-ray photoelectron spectroscopy (XPS) and powder X-ray diffraction (PXRD) analysis, respectively, giving a first indication of the mechanism of this mechanochemical reaction.
利用催化活性研磨球，在球磨系统内进行了氰化反应，同时避免了溶剂和配体的使用。此外，用六氰合铁酸钾（II）取代剧毒的氰化源，可提供更安全的反应环境。在室温下，只需 4 小时就能获得高达 90% 的产率。通过 X 射线光电子能谱（XPS）和粉末 X 射线衍射（PXRD）分析，可分别观察到氧化加成和金属转化步骤，从而首次揭示了这一机械化学反应的机理。
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