Synthesis, Spectral, and Electrochemical Properties and Antioxidant and Antiviral Activity of New 2-[5-Phenyl-6-methyl-3-aryl/getaryl-5,6-dihydro-4H-[1,2,4,5]tetrazin-1-yl]benzothiazoles

IF 0.8 4区 化学 Q4 CHEMISTRY, ORGANIC Russian Journal of Organic Chemistry Pub Date : 2024-11-06 DOI:10.1134/S1070428024080050
T. G. Fedorchenko, G. N. Lipunova, A. S. Volobueva, V. V. Zarubaev, M. S. Valova, A. V. Shchepochkin, M. A. Averkov, V. N. Tungusov, O. N. Chupakhin
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Abstract

ew 2-[5-aryl-6-methyl-3-aryl/getaryl-5,6-dihydro-4H-[1,2,4,5]tetrazin-1-yl]-benzothiazole has been synthesized from the corresponding formazanes by alkylation and subsequent cyclization of N-alkyl derivatives. The products have been characterized by 1H, 13C NMR, IR, spectroscopy, mass spectrometry, and X-ray diffraction analysis. The electrochemical properties and the antioxidant and antiviral activity of the synthesized benzothiazoles have been studied.

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新型 2-[5-苯基-6-甲基-3-芳基/getaryl-5,6-二氢-4H-[1,2,4,5]四嗪-1-基]苯并噻唑的合成、光谱和电化学性质以及抗氧化和抗病毒活性
通过 N-烷基衍生物的烷基化和环化,从相应的甲臢合成了 2-[5-芳基-6-甲基-3-芳基/得到芳基-5,6-二氢-4H-[1,2,4,5]四嗪-1-基]-苯并噻唑。通过 1H、13C NMR、IR、光谱、质谱和 X 射线衍射分析对产品进行了表征。对合成的苯并噻唑的电化学性质、抗氧化性和抗病毒活性进行了研究。
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来源期刊
CiteScore
1.40
自引率
25.00%
发文量
139
审稿时长
3-6 weeks
期刊介绍: Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.
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