[Nutrition for patients on dialysis].

Deutsche medizinische Wochenschrift (1946) Pub Date : 2024-11-01 Epub Date: 2024-11-06 DOI:10.1055/a-2199-8816
Martin K Kuhlmann, Susanne Fleig
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Abstract

Dietary recommendations for patients on dialysis are changing as our understanding of enteral microbiotal metabolism and bioavailability of nutrients from food improves.A diet low in phosphate and potassium is recommended for patients on hemodialysis. However, the absolute content does not reflect bioavailability: How much phosphate or potassium is taken up depends on food source (plant vs. animal) and to which grade it is processed. While both are nearly 100% bioavailable from industrially processed foods (additives such as dipotassium-phosphate and other salts), a much lower proportion is taken up from unprocessed plant foods high in fibre (ca. 20-40%). The DIET-HD study showed no significant association between dietary potassium and serum potassium in > 8 000 dialysis patients; and those with the highest low-processed, fresh plant-food consumption have the best survival. Dietary fibre improves colon transit time and thereby lessens symptoms of constipation. A diet low in sodium improves blood pressure and volume management in dialysis patients. The energy and protein requirements on dialysis are high: 25-35 kcal and 1-1,2 g protein per kg body weight per day (in relation to "ideal" body weight, if patient is overweight). Protein energy wasting is associated with higher stages of kidney disease, and malnutrition is associated with worse survival on dialysis. Nutritional status should be assessed on a regular basis using validated scores, and malnutrition should be addressed and treated.

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[透析患者的营养]。
随着我们对肠内微生物代谢和食物中营养物质生物利用率的认识不断提高,针对透析患者的饮食建议也在发生变化。然而,绝对含量并不能反映生物利用率:磷酸盐或钾的吸收量取决于食物来源(植物还是动物)以及食物的加工等级。工业加工食品(添加剂,如磷酸氢二钾和其他盐类)中的磷酸盐和钾的生物利用率几乎达到 100%,而未经加工的高纤维植物性食品中的磷酸盐和钾的生物利用率要低得多(约为 20-40%)。DIET-HD 研究显示,在超过 8000 名透析患者中,膳食钾与血清钾之间没有明显的关联;而那些食用低加工、新鲜植物性食物最多的患者生存率最高。膳食纤维可改善结肠转运时间,从而减轻便秘症状。低钠饮食可改善透析患者的血压和血容量管理。透析患者对能量和蛋白质的需求很高:每天每公斤体重需要 25-35 千卡能量和 1-1.2 克蛋白质(如果患者超重,则与 "理想 "体重有关)。蛋白质能量消耗与肾病的高发阶段有关,而营养不良则与透析存活率降低有关。应使用有效的评分方法定期评估营养状况,并解决和治疗营养不良问题。
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