Post-COVID syndrome and type 2 diabetes mellitus in Kazakhstan: clinical manifestations and vaccine efficacy.

IF 2.8 Q3 ENDOCRINOLOGY & METABOLISM Annals of Pediatric Endocrinology & Metabolism Pub Date : 2024-10-01 Epub Date: 2024-10-31 DOI:10.6065/apem.2346228.114
Saule Altynbekova, Zhangentkhan Abylaiuly, Svetlana Bolshakova, Timur Davlyatshin, Aizat Aimakhanova
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Abstract

Purpose: In this article, we report the results of a survey investigating post-coronavirus disease 2019 (COVID-19) syndrome in patients with type 2 diabetes mellitus and the impacts of vaccination on long-term manifestations. From February 2022 to April 2023, a survey of patients with type 2 diabetes and people without diabetes who were treated for a coronavirus infection was conducted in Kazakhstan.

Methods: Participants were invited via social media to voluntarily participate in this study. A total of 417 surveys were included in this study, comprising 212 patients with type 2 diabetes and 205 without diabetes. We compared persistent complaints after recovery in patients with and without diabetes mellitus (DM), as well as vaccination status.

Results: The results of this study on self-reported symptoms of prolonged COVID show that more than half of those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Kazakhstan have at least one persistent symptom after recovery. Based on the list of prolonged COVID-19 symptoms reported by patients with type 2 DM (T2DM), exertional dyspnoea, fatigue, respiratory discomfort, headaches, and sleep disturbances are among the most common ongoing conditions, and in many cases last more than 3 months after COVID-19.

Conclusion: Patients with T2DM experience more severe and prolonged symptoms than those without diabetes. Additionally, vaccination lowers COVID-19 hospitalization risk and decreases the need for adjusting hypoglycemic therapy, such as insulin treatment, after recovering from SARS-CoV-2 infection.

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哈萨克斯坦的后 COVID 综合征和 2 型糖尿病:临床表现和疫苗疗效。
目的:本文报告了对2型糖尿病患者冠状病毒病2019(COVID-19)后综合征的调查结果,以及接种疫苗对长期表现的影响。2022年2月至2023年4月,在哈萨克斯坦对接受冠状病毒感染治疗的2型糖尿病患者和无糖尿病患者进行了调查:方法:通过社交媒体邀请参与者自愿参与这项研究。本研究共纳入 417 份调查,其中包括 212 名 2 型糖尿病患者和 205 名非糖尿病患者。我们比较了糖尿病(DM)患者和非糖尿病(DM)患者康复后的持续投诉以及疫苗接种情况:本研究对长期慢性阻塞性肺病症状的自我报告结果显示,哈萨克斯坦一半以上的严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)感染者在康复后至少有一种持续症状。根据 2 型糖尿病(T2DM)患者报告的 COVID-19 持续症状清单,劳累性呼吸困难、疲劳、呼吸道不适、头痛和睡眠障碍是最常见的持续症状,并且在许多情况下在 COVID-19 后持续 3 个月以上:结论:与非糖尿病患者相比,T2DM 患者的症状更严重,持续时间更长。此外,接种疫苗可降低 COVID-19 的住院风险,并减少从 SARS-CoV-2 感染康复后调整降糖治疗(如胰岛素治疗)的需要。
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来源期刊
CiteScore
4.00
自引率
18.20%
发文量
59
审稿时长
24 weeks
期刊介绍: The Annals of Pediatric Endocrinology & Metabolism Journal is the official publication of the Korean Society of Pediatric Endocrinology. Its formal abbreviated title is “Ann Pediatr Endocrinol Metab”. It is a peer-reviewed open access journal of medicine published in English. The journal was launched in 1996 under the title of ‘Journal of Korean Society of Pediatric Endocrinology’ until 2011 (pISSN 1226-2242). Since 2012, the title is now changed to ‘Annals of Pediatric Endocrinology & Metabolism’. The Journal is published four times per year on the last day of March, June, September, and December. It is widely distributed for free to members of the Korean Society of Pediatric Endocrinology, medical schools, libraries, and academic institutions. The journal is indexed/tracked/covered by web sites of PubMed Central, PubMed, Emerging Sources Citation Index (ESCI), Scopus, EBSCO, EMBASE, KoreaMed, KoMCI, KCI, Science Central, DOI/CrossRef, Directory of Open Access Journals(DOAJ), and Google Scholar. The aims of Annals of Pediatric Endocrinology & Metabolism are to contribute to the advancements in the fields of pediatric endocrinology & metabolism through the scientific reviews and interchange of all of pediatric endocrinology and metabolism. It aims to reflect the latest clinical, translational, and basic research trends from worldwide valuable achievements. In addition, genome research, epidemiology, public education and clinical practice guidelines in each country are welcomed for publication. The Journal particularly focuses on research conducted with Asian-Pacific children whose genetic and environmental backgrounds are different from those of the Western. Area of specific interest include the following : Growth, puberty, glucose metabolism including diabetes mellitus, obesity, nutrition, disorders of sexual development, pituitary, thyroid, parathyroid, adrenal cortex, bone or other endocrine and metabolic disorders from infancy through adolescence.
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