Rare incidence of mucosa-associated lymphoid tissue lymphoma presenting as buccal fat pad tumor: A case report.

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL World Journal of Clinical Cases Pub Date : 2024-11-06 DOI:10.12998/wjcc.v12.i31.6506

Keitaro Miyake, Kazuhiro Hirasawa, Haruka Nishimura, Kiyoaki Tsukahara

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Abstract

Background: Mucosa-associated lymphoid tissue (MALT) lymphoma, a type of non-Hodgkin lymphoma, originates in the mucosal lining of body organs and internal cavities, including the nose, mouth, lungs, and digestive tract. The lymphoma develops when the body produces abnormal B lymphocytes. These lymphomas develop at the edge of the lymphoid tissue, called the marginal zone, and, hence, are classified as a type of marginal zone lymphomas. They are the most common type of marginal zone lymphomas although their occurrence is rare. To date, no previous cases of MALT lymphoma in the buccal fat pad have been reported.

Case summary: We report the case of a patient who presented with a mass on the frontal cheek. Magnetic resonance imaging revealed a tumor in the buccal fat pad, and histopathological and immunohistochemical findings confirmed the diagnosis of MALT lymphoma. The patient had a history of Helicobacter pylori and hepatitis C virus infection, suggesting an association between these infective agents and MALT lymphoma.

Conclusion: Consideration of MALT lymphoma is essential in the differential diagnosis of frontal cheek masses.

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罕见的粘膜相关淋巴组织淋巴瘤，表现为颊脂垫肿瘤：病例报告。

背景：粘膜相关淋巴组织（MALT）淋巴瘤粘膜相关淋巴组织（MALT）淋巴瘤是非霍奇金淋巴瘤的一种，起源于身体器官和内腔的粘膜，包括鼻腔、口腔、肺部和消化道。当人体产生异常的 B 淋巴细胞时就会形成淋巴瘤。这类淋巴瘤发生在淋巴组织的边缘，称为边缘区，因此被归类为边缘区淋巴瘤。它们是边缘区淋巴瘤中最常见的类型，但发生率很低。病例摘要：我们报告了一例因颊前部肿块就诊的患者。磁共振成像显示颊脂垫有肿瘤，组织病理学和免疫组化结果证实了 MALT 淋巴瘤的诊断。患者有幽门螺旋杆菌和丙型肝炎病毒感染史，这表明这些感染因素与MALT淋巴瘤之间存在关联：结论：在额颊部肿块的鉴别诊断中，考虑MALT淋巴瘤至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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World Journal of Clinical Cases Medicine-General Medicine

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期刊介绍： The World Journal of Clinical Cases (WJCC) is a high-quality, peer reviewed, open-access journal. The primary task of WJCC is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of clinical cases. In order to promote productive academic communication, the peer review process for the WJCC is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCC are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in clinical cases.