Tomoyuki Asada MD, PhD , Chad Z. Simon BS , Atahan Durbas MD , Myles R.J. Allen MBChB , Kevin J. DiSilvestro MD , Takashi Hirase MD, MPH , Nishtha Singh MBBS , Patawut Bovonratwet MD , Annika Bay MD , Tejas Subramanian BE , Eric Mai BS , Yeo Eun Kim BS , Maximillian K. Korsun BS , Olivia C. Tuma BS , Kasra Araghi BS , Joshua Zhang BS , Eric T. Kim BS , Cole T. Kwas BS , Amy Z. Lu BS , Avani S. Vaishnav MBBS , Sravisht Iyer MD
{"title":"Short-segment fusion versus isolated decompression in lumbar spinal canal stenosis patients with Cobb angles over 20°","authors":"Tomoyuki Asada MD, PhD , Chad Z. Simon BS , Atahan Durbas MD , Myles R.J. Allen MBChB , Kevin J. DiSilvestro MD , Takashi Hirase MD, MPH , Nishtha Singh MBBS , Patawut Bovonratwet MD , Annika Bay MD , Tejas Subramanian BE , Eric Mai BS , Yeo Eun Kim BS , Maximillian K. Korsun BS , Olivia C. Tuma BS , Kasra Araghi BS , Joshua Zhang BS , Eric T. Kim BS , Cole T. Kwas BS , Amy Z. Lu BS , Avani S. Vaishnav MBBS , Sravisht Iyer MD","doi":"10.1016/j.spinee.2024.10.007","DOIUrl":null,"url":null,"abstract":"<div><h3>BACKGROUND CONTEXT</h3><div>Lumbar decompression and short-segment lumbar fusion are standard procedures for short-segment lumbar canal stenosis, even in patients with moderate Cobb angles. Adult degenerative scoliosis is diagnosed at a threshold of 10°, and patients with coronal Cobb angles over 30° are recommended for long fusion due to global spinal deformity. However, there is a lack of research on clinical outcomes in patients with moderate coronal deformity, such as Cobb angles between 20° and 30°.</div></div><div><h3>PURPOSE</h3><div>This study aims to investigate the radiographic and clinical outcome differences between isolated decompression and short-segment interbody fusion for lumbar spinal canal stenosis in patients with moderate coronal deformity.</div></div><div><h3>STUDY DESIGN</h3><div>A retrospective analysis of a prospectively collected registry.</div></div><div><h3>PATIENT SAMPLE</h3><div>Patients with Cobb angle exceeding 20° who underwent 1- or 2- levels of lumbar surgery for lumbar canal stenosis. Patients diagnosed as spinal deformity were excluded.</div></div><div><h3>OUTCOME MEASURES</h3><div>Patient-reported outcomes included Oswestry Disability Index (ODI), VAS back, VAS leg, Short form 12 physical component score (SF-12 PCS) and Mental Component Score (SF-12 MCS), and patient-reported outcomes measurement information system physical function (PROMIS-PF) at preoperative, 12-week postoperative, and 1-year postoperative timepoints. Preoperative and postoperative spinopelvic alignment was assessed using Cobb angle, pelvic tilt, sacral slope, pelvic incidence, lumbar lordosis and PI minus LL.</div></div><div><h3>METHODS</h3><div>A propensity score-matched analysis with the overlap weighting was utilized to investigate patient-reported outcomes at 12-week and 1-year postoperatively between the surgery groups. Spinopelvic alignments were compared between preoperative and 1-year postoperative timepoint using a linear mixed-effect model.</div></div><div><h3>RESULTS</h3><div>Before overlap weighting, the two surgery groups showed significant differences in age and diagnosis. No obvious sagittal malalignment was observed (PI minus LL: decompression, 7.4° vs fusion, 11.5°). After propensity score weighting, the fusion groups exhibited significantly better ODI and VAS back at the 1-year timepoint (ODI: fusion, 16.6 vs decompression, 28.1, p=.013; VAS back: fusion, 1.5±2.1 vs decompression, 3.7±1.9, p<.001). Radiographic assessment showed that the fusion group achieved better PI minus LL compared to decompression group (15° vs 10°, p=.008).</div></div><div><h3>CONCLUSION</h3><div>In patients with degenerative scoliosis and a Cobb angle greater than 20°, short-segment lumbar fusion surgery may result in enhanced improvement for short-segment lumbar pathology compared to isolated decompression.</div></div>","PeriodicalId":49484,"journal":{"name":"Spine Journal","volume":"25 4","pages":"Pages 669-678"},"PeriodicalIF":4.7000,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine Journal","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1529943024011082","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
BACKGROUND CONTEXT
Lumbar decompression and short-segment lumbar fusion are standard procedures for short-segment lumbar canal stenosis, even in patients with moderate Cobb angles. Adult degenerative scoliosis is diagnosed at a threshold of 10°, and patients with coronal Cobb angles over 30° are recommended for long fusion due to global spinal deformity. However, there is a lack of research on clinical outcomes in patients with moderate coronal deformity, such as Cobb angles between 20° and 30°.
PURPOSE
This study aims to investigate the radiographic and clinical outcome differences between isolated decompression and short-segment interbody fusion for lumbar spinal canal stenosis in patients with moderate coronal deformity.
STUDY DESIGN
A retrospective analysis of a prospectively collected registry.
PATIENT SAMPLE
Patients with Cobb angle exceeding 20° who underwent 1- or 2- levels of lumbar surgery for lumbar canal stenosis. Patients diagnosed as spinal deformity were excluded.
OUTCOME MEASURES
Patient-reported outcomes included Oswestry Disability Index (ODI), VAS back, VAS leg, Short form 12 physical component score (SF-12 PCS) and Mental Component Score (SF-12 MCS), and patient-reported outcomes measurement information system physical function (PROMIS-PF) at preoperative, 12-week postoperative, and 1-year postoperative timepoints. Preoperative and postoperative spinopelvic alignment was assessed using Cobb angle, pelvic tilt, sacral slope, pelvic incidence, lumbar lordosis and PI minus LL.
METHODS
A propensity score-matched analysis with the overlap weighting was utilized to investigate patient-reported outcomes at 12-week and 1-year postoperatively between the surgery groups. Spinopelvic alignments were compared between preoperative and 1-year postoperative timepoint using a linear mixed-effect model.
RESULTS
Before overlap weighting, the two surgery groups showed significant differences in age and diagnosis. No obvious sagittal malalignment was observed (PI minus LL: decompression, 7.4° vs fusion, 11.5°). After propensity score weighting, the fusion groups exhibited significantly better ODI and VAS back at the 1-year timepoint (ODI: fusion, 16.6 vs decompression, 28.1, p=.013; VAS back: fusion, 1.5±2.1 vs decompression, 3.7±1.9, p<.001). Radiographic assessment showed that the fusion group achieved better PI minus LL compared to decompression group (15° vs 10°, p=.008).
CONCLUSION
In patients with degenerative scoliosis and a Cobb angle greater than 20°, short-segment lumbar fusion surgery may result in enhanced improvement for short-segment lumbar pathology compared to isolated decompression.
期刊介绍:
The Spine Journal, the official journal of the North American Spine Society, is an international and multidisciplinary journal that publishes original, peer-reviewed articles on research and treatment related to the spine and spine care, including basic science and clinical investigations. It is a condition of publication that manuscripts submitted to The Spine Journal have not been published, and will not be simultaneously submitted or published elsewhere. The Spine Journal also publishes major reviews of specific topics by acknowledged authorities, technical notes, teaching editorials, and other special features, Letters to the Editor-in-Chief are encouraged.