Chronic pain in older adults with disabilities is associated with cognitive impairment-a prospective cohort study.

Hiroya Honda, Ryota Ashizawa, Yuto Kameyama, Yoshinobu Yoshimoto
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Abstract

Background: Chronic pain may be an important factor influencing cognitive impairment; however, there is limited research on that link in older adults with disabilities. We aimed to determine the association between chronic pain and cognitive impairment in older adults with disabilities.

Methods: This 24-month prospective cohort study involved 143 Japanese older adults (≥65 years of age) with long-term care insurance. Chronic pain was defined as pain persisting for ≥3 months, and cognitive impairment was defined as a Mini-Mental State Examination score ≤ 23. We employed logistic regression analysis with chronic pain as the independent variable and cognitive impairment as the dependent variable after propensity score matching (PSM).

Results: Sixty-six participants were selected using PSM, and logistic regression analysis showed that chronic pain was significantly associated with cognitive impairment (odds ratio: 4.103, 95% confidence interval: 1.455-11.567, P = 0.008).

Conclusion: To prevent cognitive impairment in older adults with disabilities, the management of chronic pain should be considered, as they are related.

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残疾老年人的慢性疼痛与认知障碍有关--一项前瞻性队列研究。
背景:慢性疼痛可能是影响认知障碍的一个重要因素;然而,有关残疾老年人慢性疼痛与认知障碍之间关系的研究却很有限。我们旨在确定残疾老年人的慢性疼痛与认知障碍之间的关系:这项为期 24 个月的前瞻性队列研究涉及 143 名有长期护理保险的日本老年人(年龄≥65 岁)。慢性疼痛的定义是疼痛持续时间≥3 个月,认知障碍的定义是迷你精神状态检查评分≤23 分。我们采用了逻辑回归分析,以慢性疼痛为自变量,认知障碍为因变量,并进行了倾向得分匹配(PSM):逻辑回归分析表明,慢性疼痛与认知障碍显著相关(几率比:4.103,95% 置信区间:1.455-11.567,P = 0.008):结论:为预防残疾老年人出现认知障碍,应考虑对慢性疼痛进行管理,因为它们之间存在关联。
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