Endovascular Aneurysm Repair Versus Open Surgical Repair in Treating Abdominal Aortic Aneurysm.

IF 1 Q3 MEDICINE, GENERAL & INTERNAL Cureus Pub Date : 2024-11-05 eCollection Date: 2024-11-01 DOI:10.7759/cureus.73066
James R Vienneau, Camden I Burns, Anto Boghokian, Varun Soti
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Abstract

Abdominal aortic aneurysm (AAA) denotes an abdominal aorta dilation exceeding 3 cm, typically asymptomatic until rupture, posing severe consequences, including fatality. Therefore, continual screening is imperative, and surgical intervention is recommended upon reaching a diameter of 5.5 cm to prevent rupture. The primary surgical approaches are open surgical repair or open repair (OR) and endovascular aneurysm repair (EVAR). This review juxtaposes EVAR's short- and long-term effectiveness, safety, and perioperative complications in AAA patients versus OR, elucidating clinical benefits and avenues for further research. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, an extensive literature review was conducted using the PubMed and Clinicaltrials.gov databases. The review specifically focused on clinical studies directly comparing EVAR versus OR. The comprehensive literature review revealed that EVAR confers a survival advantage for up to four years post-procedure. However, the benefit shifts to OR after four to eight years due to aneurysm-related complications, such as ruptures, underscoring the necessity of lifelong post-EVAR monitoring. Following EVAR, AAA patients necessitate significantly more frequent secondary interventions due to graft-related issues, including endoleaks, thereby escalating long-term complexity and care costs. Conversely, following OR, a notably higher proportion of patients require mechanical ventilation and blood transfusions and experience prolonged intensive-care and mid-care unit stays, consequently extending hospitalization. After EVAR, patients recover substantially faster, returning to normal activities sooner. Nonetheless, the long-term quality of life between the two procedures becomes comparable. While EVAR presents itself as a less invasive alternative to OR, especially for high surgical risk patients, the imperative of long-term surveillance and the risk of secondary interventions pose significant challenges. Advancements in EVAR technology and technique are broadening its utility. Yet, continual research is crucial to optimize patient selection, improve long-term outcomes, and ensure that EVAR's benefits outweigh the risks. Therefore, choosing EVAR over OR in treating AAA patients must factor in a patient's overall health, anatomical considerations, and the probability of long-term success.

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治疗腹主动脉瘤的血管内动脉瘤修补术与开放手术修补术的比较
腹主动脉瘤(AAA)是指腹主动脉扩张超过 3 厘米,在破裂前通常无症状,会造成包括死亡在内的严重后果。因此,必须持续进行筛查,并建议在直径达到 5.5 厘米时进行手术干预,以防止破裂。主要的手术方法有开放性手术修复或开放性修复(OR)和血管内动脉瘤修复(EVAR)。本综述将 EVAR 对 AAA 患者的短期和长期疗效、安全性和围手术期并发症与 OR 进行对比,阐明临床益处和进一步研究的途径。根据《系统综述和元分析首选报告项目》指南,我们使用 PubMed 和 Clinicaltrials.gov 数据库进行了广泛的文献综述。该综述特别关注直接比较 EVAR 与手术室手术的临床研究。综合文献综述显示,EVAR 在术后四年内具有生存优势。然而,由于动脉瘤相关并发症(如破裂)的影响,EVAR术后四至八年的生存优势将转为手术治疗,这就强调了EVAR术后终生监测的必要性。EVAR术后,由于移植物相关问题(包括内漏),AAA患者需要更频繁地进行二次干预,从而增加了长期复杂性和护理成本。相反,在手术室手术后,需要机械通气和输血的患者比例明显增加,重症监护室和中监护室的住院时间延长,从而延长了住院时间。EVAR 术后,患者的恢复速度大大加快,可以更快地恢复正常活动。不过,两种手术的长期生活质量不相上下。虽然 EVAR 是手术室之外的一种创伤较小的替代手术,尤其是对于手术风险较高的患者来说,但长期监测的必要性和二次干预的风险也带来了巨大的挑战。EVAR 技术和技巧的进步正在扩大其应用范围。然而,持续的研究对于优化患者选择、改善长期疗效以及确保 EVAR 的益处大于风险至关重要。因此,在治疗 AAA 患者时,选择 EVAR 而非手术治疗必须考虑患者的总体健康状况、解剖学因素以及长期成功的可能性。
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