One-pot multicomponent photo-induced eosin-Y catalyzed synthesis of 2-amino oxa/thiazine derivatives

IF 1.5 4区 化学 Q3 CHEMISTRY, ORGANIC Tetrahedron Letters Pub Date : 2024-11-06 DOI:10.1016/j.tetlet.2024.155339
Km Garima , Vishal Srivastava , Praveen P. Singh , Pravin K. Singh
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Abstract

An effective and advantageous one-pot multicomponent photo-induced methodology has been developed for the synthesis of biologically potent 2-amino-4H-1,3-oxa/thiazine from substituted benzaldehyde, ethynylbenzene and urea/thiourea catalyzed by eosin-Y at room temperature using EtOH as a green solvent with wide range of applications in pharmaceutical and agriculture industries. This proposed work emphasizes to investigate an accessible, safe, easy and convenient method for the synthesis of 2-amino oxa/thiazine derivatives with good to excellent yield.

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单锅多组分光诱导曙红-Y 催化合成 2-氨基氧杂/噻嗪衍生物
在常温下,以 ETOH 为绿色溶剂,在 eosin-Y 催化下,以取代的苯甲醛、乙炔苯和尿素/硫脲为原料,开发了一种有效且有利的单锅多组分光诱导方法,用于合成具有生物活性的 2-氨基-4H-1,3-氧杂/噻嗪,该方法在制药和农业领域具有广泛的应用。本研究的重点是研究一种容易获得、安全、简单、方便的方法来合成 2-氨基氧杂噻嗪/噻嗪衍生物,并获得良好甚至优异的产率。
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来源期刊
Tetrahedron Letters
Tetrahedron Letters 化学-有机化学
CiteScore
3.50
自引率
5.60%
发文量
521
审稿时长
28 days
期刊介绍: Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
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