Km Garima , Vishal Srivastava , Praveen P. Singh , Pravin K. Singh
{"title":"One-pot multicomponent photo-induced eosin-Y catalyzed synthesis of 2-amino oxa/thiazine derivatives","authors":"Km Garima , Vishal Srivastava , Praveen P. Singh , Pravin K. Singh","doi":"10.1016/j.tetlet.2024.155339","DOIUrl":null,"url":null,"abstract":"<div><div>An effective and advantageous one-pot multicomponent photo-induced methodology has been developed for the synthesis of biologically potent 2-amino-4<em>H</em>-1,3-oxa/thiazine from substituted benzaldehyde, ethynylbenzene and urea/thiourea catalyzed by eosin-Y at room temperature using EtOH as a green solvent with wide range of applications in pharmaceutical and agriculture industries. This proposed work emphasizes to investigate an accessible, safe, easy and convenient method for the synthesis of 2-amino oxa/thiazine derivatives with good to excellent yield.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040403924004349","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
An effective and advantageous one-pot multicomponent photo-induced methodology has been developed for the synthesis of biologically potent 2-amino-4H-1,3-oxa/thiazine from substituted benzaldehyde, ethynylbenzene and urea/thiourea catalyzed by eosin-Y at room temperature using EtOH as a green solvent with wide range of applications in pharmaceutical and agriculture industries. This proposed work emphasizes to investigate an accessible, safe, easy and convenient method for the synthesis of 2-amino oxa/thiazine derivatives with good to excellent yield.
期刊介绍:
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.