Comment on “Perception of social inclusion/exclusion and response inhibition in adolescents with past suicide attempt: a multidomain task-based fMRI study.” by Gifuni et al.

IF 10.1 1区 医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Psychiatry Pub Date : 2024-11-08 DOI:10.1038/s41380-024-02745-9
Emilie Olié, Philippe Courtet
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就 Gifuni 等人撰写的 "自杀未遂青少年的社会包容/排斥感知和反应抑制:基于多域任务的 fMRI 研究 "发表评论。
Gifuni等人[1]进行的fMRI研究调查了自杀企图者与精神病患者和健康对照组相比在社会包容/排斥任务中的神经反应。作者强调了一个重要发现,即与对照组相比,自杀企图者在包容与对照条件(即被动观看或内隐社会排斥(ISE))下左侧岛叶的激活率较低。此外,他们还报告说,较高的社会排斥感(通过需要威胁量表测量)与包含-对照对比期间的脑岛活动相关。首先,自杀企图者脑岛活动的减少可能与消极状态的一般处理有关,而不是社会排斥的特定影响。事实上,社会排斥感与脑岛活动相关,但也与抑郁程度相关。有趣的是,Caceda 等人[2] 发现,在包容-休息过程中,前脑岛反应与抑郁严重程度之间存在显著相关性。
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来源期刊
Molecular Psychiatry
Molecular Psychiatry 医学-精神病学
CiteScore
20.50
自引率
4.50%
发文量
459
审稿时长
4-8 weeks
期刊介绍: Molecular Psychiatry focuses on publishing research that aims to uncover the biological mechanisms behind psychiatric disorders and their treatment. The journal emphasizes studies that bridge pre-clinical and clinical research, covering cellular, molecular, integrative, clinical, imaging, and psychopharmacology levels.
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