Selenium micro-encapsulation: Innovative strategies for supplementing plant-based beverages

IF 5.4 2区 医学 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Biomaterials Science & Engineering Pub Date : 2024-11-10 DOI:10.1016/j.foodchem.2024.141993
José Luan da Paixão Teixeira, Ana Paula Rebellato, Raquel Fernanda Milani, Izabela Dutra Alvim, Marcelo Antonio Morgano
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Abstract

Selenium (Se) is an essential micronutrient for humans, and one of the new strategies to increase its intake is to fortify foodstuff with Se-bioaccessible species. This study aimed to produce Se-microparticles (selenate, selenite and Se-organic) using combined methods of microencapsulation; fortify commercial plant-based beverages (PBBs); evaluate the stability of microparticles; and estimate the bioaccessibility of Se and its contribution to the Recommended Daily Intake (RDA). Samples and bioaccessible fractions were submitted to acid digestion and Se levels (total and bioaccessible) were quantified by ICP-MS. The bioaccessibility of the Se-microparticles produced was estimated using an in vitro method under standardized conditions (INFOGEST). During the storage period, the microparticles maintained their stability and similar size. The PBBs fortified with Se-microparticles presented high bioaccessibility (77–94 %); being superior, in comparison, to the traditional fortification (Se-isolated salts). Thus, the results suggest promising perspectives for Se-supplementation in PBBs to meet nutritional needs effectively.

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硒微胶囊:补充植物饮料的创新战略
硒(Se)是人类必需的微量营养元素,而增加硒摄入量的新策略之一就是在食品中添加可被生物利用的硒元素。本研究旨在采用微胶囊化的综合方法生产硒微粒(硒酸盐、亚硒酸盐和硒有机物);强化商业植物饮料(PBBs);评估微粒的稳定性;估算硒的生物可及性及其对每日推荐摄入量(RDA)的贡献。将样品和生物可利用部分进行酸消化,并通过 ICP-MS 对 Se 含量(总含量和生物可利用含量)进行定量。采用标准化条件下的体外方法(INFOGEST)估算了所产生的硒微粒的生物可及性。在储存期间,微颗粒保持了稳定性和相似的大小。使用 Se 微颗粒强化的多溴联苯具有很高的生物可接受性(77-94%);与传统的强化方法(Se 分离盐)相比更胜一筹。因此,研究结果表明,在多溴联苯中添加硒以有效满足营养需求的前景广阔。
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来源期刊
ACS Biomaterials Science & Engineering
ACS Biomaterials Science & Engineering Materials Science-Biomaterials
CiteScore
10.30
自引率
3.40%
发文量
413
期刊介绍: ACS Biomaterials Science & Engineering is the leading journal in the field of biomaterials, serving as an international forum for publishing cutting-edge research and innovative ideas on a broad range of topics: Applications and Health – implantable tissues and devices, prosthesis, health risks, toxicology Bio-interactions and Bio-compatibility – material-biology interactions, chemical/morphological/structural communication, mechanobiology, signaling and biological responses, immuno-engineering, calcification, coatings, corrosion and degradation of biomaterials and devices, biophysical regulation of cell functions Characterization, Synthesis, and Modification – new biomaterials, bioinspired and biomimetic approaches to biomaterials, exploiting structural hierarchy and architectural control, combinatorial strategies for biomaterials discovery, genetic biomaterials design, synthetic biology, new composite systems, bionics, polymer synthesis Controlled Release and Delivery Systems – biomaterial-based drug and gene delivery, bio-responsive delivery of regulatory molecules, pharmaceutical engineering Healthcare Advances – clinical translation, regulatory issues, patient safety, emerging trends Imaging and Diagnostics – imaging agents and probes, theranostics, biosensors, monitoring Manufacturing and Technology – 3D printing, inks, organ-on-a-chip, bioreactor/perfusion systems, microdevices, BioMEMS, optics and electronics interfaces with biomaterials, systems integration Modeling and Informatics Tools – scaling methods to guide biomaterial design, predictive algorithms for structure-function, biomechanics, integrating bioinformatics with biomaterials discovery, metabolomics in the context of biomaterials Tissue Engineering and Regenerative Medicine – basic and applied studies, cell therapies, scaffolds, vascularization, bioartificial organs, transplantation and functionality, cellular agriculture
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