Amniotic Membrane Transplantation: Clinical Applications in Enhancing Wound Healing and Tissue Regeneration.

4区医学 Q2 Biochemistry, Genetics and Molecular Biology Advances in experimental medicine and biology Pub Date : 2024-11-09 DOI:10.1007/5584_2024_834

Mutali Musa, Ekele Chukwuyem, Ehimare Enaholo, Ifeoma Esekea, Eghosasere Iyamu, Fabiana D'Esposito, Daniele Tognetto, Caterina Gagliano, Marco Zeppieri

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Abstract

Chronic wounds and non-healing tissue defects pose significant clinical challenges, necessitating innovative therapeutic approaches. A comprehensive literature review of amniotic membrane transplantation for wound healing and tissue repair evaluates the efficacy and safety of amniotic membrane transplantation in enhancing wound healing and tissue repair. Amniotic membranes promote wound closure and reduce inflammation and scarring via abundant growth factors, cytokines, and extracellular matrix components, which foster conducive environments for tissue regeneration. Amniotic membrane transplantation is effective in various medical disciplines, including ophthalmology, dermatology, and orthopedics. Low immunogenicity and anti-microbial properties ensure their safe application. Amniotic membrane transplantation offers a promising therapeutic approach for wound healing and tissue repair, and further research is warranted to explore its regenerative potential fully.

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羊膜移植：加强伤口愈合和组织再生的临床应用》。

慢性伤口和不愈合的组织缺损给临床带来了巨大挑战，需要创新的治疗方法。有关羊膜移植促进伤口愈合和组织修复的全面文献综述评估了羊膜移植在促进伤口愈合和组织修复方面的有效性和安全性。羊膜通过丰富的生长因子、细胞因子和细胞外基质成分促进伤口闭合，减少炎症和疤痕，为组织再生创造有利环境。羊膜移植在眼科、皮肤科和骨科等多个医学领域都很有效。低免疫原性和抗微生物特性确保了其应用的安全性。羊膜移植为伤口愈合和组织修复提供了一种前景广阔的治疗方法，需要进一步研究以充分挖掘其再生潜力。

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来源期刊

Advances in experimental medicine and biology 医学-医学：研究与实验

CiteScore

5.90

自引率

0.00%

发文量

465

审稿时长

2-4 weeks

期刊介绍： Advances in Experimental Medicine and Biology provides a platform for scientific contributions in the main disciplines of the biomedicine and the life sciences. This series publishes thematic volumes on contemporary research in the areas of microbiology, immunology, neurosciences, biochemistry, biomedical engineering, genetics, physiology, and cancer research. Covering emerging topics and techniques in basic and clinical science, it brings together clinicians and researchers from various fields.