Structural analysis of a non-pathogenic hare calicivirus capsid bound to a histo-blood group antigen co-factor.

IF 4 2区医学 Q2 VIROLOGY Journal of Virology Pub Date : 2024-11-08 DOI:10.1128/jvi.01675-24

Grant S Hansman, Todd Reese, Marie Pancera, Penny A Rudd, Veronika Masic, Thomas Haselhorst, Mark von Itzstein

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与组织血型抗原辅助因子结合的非致病性野兔卡里科病毒包囊的结构分析。

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来源期刊

Journal of Virology 医学-病毒学

CiteScore

10.10

自引率

7.40%

发文量

906

审稿时长

1 months

期刊介绍： Journal of Virology (JVI) explores the nature of the viruses of animals, archaea, bacteria, fungi, plants, and protozoa. We welcome papers on virion structure and assembly, viral genome replication and regulation of gene expression, genetic diversity and evolution, virus-cell interactions, cellular responses to infection, transformation and oncogenesis, gene delivery, viral pathogenesis and immunity, and vaccines and antiviral agents.

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Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress pattern. Structural analysis of a non-pathogenic hare calicivirus capsid bound to a histo-blood group antigen co-factor. Dengue virus NS1 leads to downregulation of HNF4 alpha in liver cells resulting in a decrease in coagulation factors I, V, X, and XIII, contributing to coagulopathy. Examination of respiratory syncytial virus fusion protein proteolytic processing and roles of the P27 domain. Identification of stimuli that enhance human herpesvirus 6A (HHV-6A) replication and reconstitution.