Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-11-08 DOI:10.1080/03007995.2024.2427882
Alessandra Marchese, Rocco Accogli, Annalisa Frizzelli, Alessandro De Simoni, Olha Bondarenko, Roberta Pisi, Gaetano Caramori, Giovanna Pelà, Maria Majori, Letizia Gnetti, Agnese Aluia, Lorenzo D'Aloisio, Alfredo Chetta, Marina Aiello
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Abstract

Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small and medium-caliber blood vessels.

Case report: In this report we present an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms.

Conclusions: our case appears interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature.

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ANCA 阳性 EGPA 发病伴双侧胸腔积液:病例报告。
简介嗜酸性粒细胞肉芽肿伴多血管炎(EGPA)是一种多系统、免疫介导的疾病,多发于哮喘和嗜酸性粒细胞增多症患者。病例报告:在本报告中,我们介绍了一例不寻常的 EGPA 临床病例,患者的抗中性粒细胞胞浆抗体呈阳性,表现为双侧胸腔积液。诊断是通过实验室评估和支气管活检确诊的。结论:考虑到文献中记载的 EGPA 患者胸腔积液的证据有限,我们的病例显得非常有趣。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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