Health Knowledge in Adolescent Childhood Cancer Survivors at High Risk for Therapy-Related Cardiotoxicity.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-11-07 DOI:10.1089/jayao.2024.0116
Sanyukta K Janardan, Ann C Mertens, Karen E Effinger
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Abstract

Childhood cancer survivors' (CCS) knowledge about late effects can promote positive health behaviors and autonomy. Cardiotoxicity is a major source of morbidity, which can be mitigated through exercise. Descriptive and Fisher's exact statistics were used to characterize health knowledge and physical activity in CCS ≥13 years at high risk for cardiotoxicity. Of 16 CCS (mean age 17.0 ± 2.1 years), 3 (18.8%) identified previous anthracycline exposure, and 5 (31.2%) had adequate physical activity. Of survivors <18 years, 82% had poor late effects knowledge (p = 0.005). Knowledge was not associated with physical activity (p = 0.60). Interventions are needed to improve late effects knowledge in adolescent CCS.

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治疗相关心脏毒性高风险青少年儿童癌症幸存者的健康知识。
儿童癌症幸存者(CCS)对晚期影响的了解可以促进积极的健康行为和自主性。心脏毒性是发病率的一个主要来源,可以通过锻炼来减轻。我们采用描述性统计和费雪精确统计来描述年龄≥13 岁、有心脏毒性高风险的儿童癌症患者的健康知识和体育锻炼情况。在16名CCS(平均年龄为17.0 ± 2.1岁)中,有3人(18.8%)曾接触过蒽环类药物,5人(31.2%)有足够的体育锻炼。幸存者中P = 0.005)。知识与体育锻炼无关(p = 0.60)。需要采取干预措施来提高青少年对晚期效应的认识。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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