Calprotectin Correlates with Reduced Level of LVEF and Occurrence of Cardiac Arrhythmia in STEMI Patients.

IF 1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Advanced biomedical research Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI:10.4103/abr.abr_438_23

Habib Haybar, Babak Ramezani, Ahmad Reza Assareh, Ali Kardooni, Shirin Azizidoost

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Abstract

Background: Calprotectin is recognized as a promising prognostic as well as a diagnostic marker of cardiac disorders. In the present study, we aimed to survey the efficiency of serum calprotectin levels in anticipating the severity of coronary artery disease (CAD) along with in-hospital major adverse cardiovascular events (MACE) in patients with ST-segment elevation (STEMI) underlying primary percutaneous coronary intervention (PCI).

Materials and methods: A total of 97 patients with STEMI participated and were evaluated for in-hospital MACE for possible correlation with serum calprotectin.

Results: Increased levels of serum calprotectin showed positive and negative correlation with severity of coronary arteries and left ventricular ejection fraction (LVEF) of STEMI patients, respectively. Regarding in-hospital MACE, only arrhythmia showed a significant relationship in patients with high calprotectin levels.

Conclusion: High calprotectin levels may be a prognostic marker for occluded artery and LVEF in STEMI patients.

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钙粘蛋白与 STEMI 患者 LVEF 水平降低和心律失常的发生有关。

背景：钙黏蛋白被认为是一种很有前景的心脏疾病预后和诊断标志物。在本研究中，我们旨在调查血清钙黏蛋白水平在预测ST段抬高（STEMI）患者冠状动脉疾病（CAD）严重程度以及院内主要不良心血管事件（MACE）方面的效率：共有97名STEMI患者参与了研究，并评估了院内MACE与血清钙蛋白的相关性：结果：血清钙黏蛋白水平升高分别与 STEMI 患者冠状动脉严重程度和左心室射血分数（LVEF）呈正相关和负相关。在院内MACE方面，只有心律失常与钙粘蛋白水平高的患者有显著关系：结论：高钙粘蛋白水平可能是 STEMI 患者闭塞动脉和 LVEF 的预后指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced biomedical research

CiteScore

0.90

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0.00%

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