{"title":"An AIE probe for simultaneous monitoring of endogenous and exogenous hypochlorite and Zn<sup>2+</sup> at dual channels in living cells.","authors":"Na-Na Li, Ye-Jin Liang, Hai-Long Li, Ting-Ting Wei, Zhan-Bin Jin, Xing-Yu Xu, Hai-Xian Ren, Wan-Ying Lin, Zi-Ao Zong, Yao Zuo","doi":"10.1039/d4ay01613k","DOIUrl":null,"url":null,"abstract":"<p><p>Zn<sup>2+</sup> and ClO<sup>-</sup> may be associated with a variety of pathologies, and their simultaneous measurement is crucial for disease diagnosis and environmental protection. In this work, we synthesized an independent AIE probe, HNTE, through a one step reaction. The probe HNTE displayed a distinctive fluorescence color change from deep yellow to blue for ClO<sup>-</sup> and to green for Zn<sup>2+</sup>. More importantly, the probe HNTE could simultaneously detect endogenous and exogenous ClO<sup>-</sup> and Zn<sup>2+</sup> in living cells colorimetrically <i>via</i> the blue and green channels.</p>","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical Methods","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ay01613k","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Zn2+ and ClO- may be associated with a variety of pathologies, and their simultaneous measurement is crucial for disease diagnosis and environmental protection. In this work, we synthesized an independent AIE probe, HNTE, through a one step reaction. The probe HNTE displayed a distinctive fluorescence color change from deep yellow to blue for ClO- and to green for Zn2+. More importantly, the probe HNTE could simultaneously detect endogenous and exogenous ClO- and Zn2+ in living cells colorimetrically via the blue and green channels.