Analysis of the efficacy of different amounts of parathyroid grafts in the treatment of secondary hyperparathyroidism.

IF 3.3 3区医学 Q3 ENDOCRINOLOGY & METABOLISM BMC Endocrine Disorders Pub Date : 2024-11-12 DOI:10.1186/s12902-024-01777-0

Wentan Chen, Ge Zhou

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Abstract

Purpose: This study compares the efficacy of two different ranges of parathyroid transplantation weights with the aim of determining a preferable range for transplantation weight.

Methods: From May 2018 to June 2023, 79 patients underwent total parathyroidectomy with autotransplantation. Demographic data, symptoms, and pre- or postoperative biochemical indicators were compared between two different ranges of parathyroid transplantation weights.

Results: All 79 surgeries were successful, with a total of 316 parathyroid glands reported among the patients. The patients were diagnosed with parathyroid hyperplasia. Postoperatively, itching, bone pain, and muscle weakness disappeared, while serum parathyroid hormone and phosphate levels significantly decreased. With an average follow-up of 12 months, no transplant-dependent recurrence was observed.

Conclusion: Parathyroid transplantation with a weight of 30-50 mg is a feasible, safe, and effective surgical approach.

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分析不同数量的甲状旁腺移植物在治疗继发性甲状旁腺功能亢进症中的疗效。

目的：本研究比较了两种不同范围的甲状旁腺移植重量的疗效，旨在确定移植重量的优选范围：2018年5月至2023年6月，79名患者接受了甲状旁腺全切除术并进行了自体移植。比较了两种不同范围的甲状旁腺移植重量的人口统计学数据、症状和术前或术后生化指标：79例手术全部成功，患者共报告了316个甲状旁腺。患者被诊断为甲状旁腺增生症。术后，瘙痒、骨痛和肌肉无力症状消失，血清甲状旁腺激素和磷酸盐水平显著下降。平均随访12个月，未发现移植依赖性复发：结论：重量为30-50毫克的甲状旁腺移植是一种可行、安全且有效的手术方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-

CiteScore

4.40

自引率

0.00%

发文量

280

审稿时长

>12 weeks

期刊介绍： BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.