Current knowledge on Inquilinus limosus, a scarcely researched human pathogen.

IF 4 2区 生物学 Q2 MICROBIOLOGY BMC Microbiology Pub Date : 2024-11-13 DOI:10.1186/s12866-024-03617-6
Oluwafemi M Akinnurun, Thomas Riedel, Stephanie Müller, Boyke Bunk, Percy Schröttner
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Abstract

Inquilinus limosus belongs to the class of the Alphaproteobacteria and was first described in 2002. So far, the species has mainly been isolated from respiratory specimens of patients with cystic fibrosis. A main characteristic of Inquilinus limosus is the prolonged time until bacterial colony growth is detectable. As the defined incubation times in many laboratories are too short to detect the growth of Inquilinus limosus, it is likely that the species is less frequently detected in the clinical setting than it actually occurs. This also explains why there are currently only very few data on the incidence available. Furthermore, as an uncommon pathogen, Inquilinus limosus may be familiar to only a few specialised clinicians. Due to these reasons, only little research (e.g. case reports and research papers) have been published on this species to date. However, given that a clear human pathogenic significance can be deduced from the existing literature, we have decided to present the current state of knowledge in this review and to address further aspects for the future elucidation of the pathogenesis of Inquilinus limosus.

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目前对 Inquilinus limosus(一种研究很少的人类病原体)的了解。
Inquilinus limosus 属于阿尔法蛋白细菌,于 2002 年首次被描述。迄今为止,该菌种主要是从囊性纤维化患者的呼吸道标本中分离出来的。Inquilinus limosus 的一个主要特征是细菌菌落生长的检测时间较长。由于许多实验室规定的培养时间太短,无法检测到灰飞蓟马的生长,因此在临床环境中检测到灰飞蓟马的频率很可能低于实际发生的频率。这也解释了为什么目前只有很少的发病率数据。此外,作为一种不常见的病原体,Inquilinus limosus 可能只为少数专业临床医生所熟悉。由于这些原因,迄今为止有关该物种的研究(如病例报告和研究论文)很少。不过,鉴于从现有文献中可以推断出该病原体对人类具有明显的致病意义,我们决定在本综述中介绍目前的知识状况,并进一步探讨今后如何阐明石灰茵的致病机理。
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来源期刊
BMC Microbiology
BMC Microbiology 生物-微生物学
CiteScore
7.20
自引率
0.00%
发文量
280
审稿时长
3 months
期刊介绍: BMC Microbiology is an open access, peer-reviewed journal that considers articles on analytical and functional studies of prokaryotic and eukaryotic microorganisms, viruses and small parasites, as well as host and therapeutic responses to them and their interaction with the environment.
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