Atrial fibrillation in Black American patients: A review of genetics, risk factors, and outcomes.

IF 5.6 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Heart rhythm Pub Date : 2024-11-06 DOI:10.1016/j.hrthm.2024.10.074
Aseel Houmsse, Nipun Malhotra, Sakima A Smith, Mona El Refaey
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Abstract

Atrial fibrillation (AF), the most common arrhythmia in the United States, affects 6 million Americans, with numbers projected to increase to 12 million by 2030. A racial paradox difference in the incidence and prevalence of AF exists between Black and White Americans. Black Americans are less prone than White Americans to development of AF, but they display a higher burden of modifiable risk factors for cardiovascular disease and higher rates of ischemic stroke. Data pertaining to the American Heart Association Life's Simple 7 (LS7) health metrics show that Black Americans have suboptimal LS7 scores compared with White Americans on average despite lower genetic predisposition to AF. This trend suggests the impact of cardiovascular health on the development and progression of AF. Social, genetic, and lifestyle risk factors have been shown to play a role in the racial paradox and AF outcomes in Black Americans. This review summarizes factors contributing to the racial paradox and discusses suggestions for improved health outcomes in Black Americans with AF.

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美国黑人心房颤动患者:遗传学、风险因素和结果综述。
心房颤动(房颤)是美国最常见的心律失常,影响着 600 万美国人,预计到 2030 年将增至 1200 万人。美国黑人和白人在心房颤动的发病率和流行率方面存在种族差异。美国黑人比美国白人更不容易患心房颤动,但他们患心血管疾病的可改变风险因素更高,缺血性中风的发病率也更高。美国心脏协会 "生命简单 7"(LS7)健康指标的相关数据显示,尽管心房颤动的遗传易感性较低,但与美国白人相比,美国黑人的 LS7 平均得分并不理想。这一趋势表明心血管健康对心房颤动的发生和发展有影响。社会、遗传和生活方式等风险因素已被证明在美国黑人的种族悖论和心房颤动结果中发挥作用。本综述将总结导致种族悖论的因素,并讨论改善患有心房颤动的美国黑人健康状况的建议。
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来源期刊
Heart rhythm
Heart rhythm 医学-心血管系统
CiteScore
10.50
自引率
5.50%
发文量
1465
审稿时长
24 days
期刊介绍: HeartRhythm, the official Journal of the Heart Rhythm Society and the Cardiac Electrophysiology Society, is a unique journal for fundamental discovery and clinical applicability. HeartRhythm integrates the entire cardiac electrophysiology (EP) community from basic and clinical academic researchers, private practitioners, engineers, allied professionals, industry, and trainees, all of whom are vital and interdependent members of our EP community. The Heart Rhythm Society is the international leader in science, education, and advocacy for cardiac arrhythmia professionals and patients, and the primary information resource on heart rhythm disorders. Its mission is to improve the care of patients by promoting research, education, and optimal health care policies and standards.
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