Risk of uveitis among E-Cigarette Users: a multi-institutional TriNetX study.

IF 13.1 1区 医学 Q1 OPHTHALMOLOGY Ophthalmology Pub Date : 2024-11-11 DOI:10.1016/j.ophtha.2024.11.008
Alan Y Hsu, Yu-Hsun Wang, Ning-Yi Hsia, Chun-Ting Lai, Hou-Ting Kuo, Bing-Qi Wu, Chun-Ju Lin, Chun-Chi Chiang, Yi-Ching Shao, Huan-Sheng Chen, Yi-Yu Tsai, James Cheng-Chung Wei
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Abstract

Purpose: To determine the risk of uveitis among e-cigarette users METHODS: The TriNetX database was used to recruit adult patients with and without a history of e-cigarette usage. The primary outcome was the incidence of new-onset uveitis.

Results: E-cigarette users were associated with an increased risk for uveitis compared to non-users (HR: 2.53, CI: 2.33-2.76). Subgroup analysis revealed an increased risk of uveitis among e-cigarette users aged 18-39 years (HR: 2.59, CI: 2.11-3.17), 40-64 years (HR: 2.20, CI: 1.95-2.48) and ≥65 years (HR: 3.15, CI: 2.72-3.64).

Conclusions: An increased risk for uveitis was seen among e-cigarette users compared to non-users.

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电子烟使用者患葡萄膜炎的风险:TriNetX 多机构研究。
目的:确定电子烟使用者患葡萄膜炎的风险 方法:使用 TriNetX 数据库招募有和无电子烟使用史的成年患者。主要结果是新发葡萄膜炎的发病率:结果:与未使用电子烟者相比,使用电子烟者患葡萄膜炎的风险增加(HR:2.53,CI:2.33-2.76)。亚组分析显示,18-39 岁(HR:2.59,CI:2.11-3.17)、40-64 岁(HR:2.20,CI:1.95-2.48)和≥65 岁(HR:3.15,CI:2.72-3.64)的电子烟使用者患葡萄膜炎的风险增加:结论:与不使用电子烟的人相比,使用电子烟的人患葡萄膜炎的风险增加。
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来源期刊
Ophthalmology
Ophthalmology 医学-眼科学
CiteScore
22.30
自引率
3.60%
发文量
412
审稿时长
18 days
期刊介绍: The journal Ophthalmology, from the American Academy of Ophthalmology, contributes to society by publishing research in clinical and basic science related to vision.It upholds excellence through unbiased peer-review, fostering innovation, promoting discovery, and encouraging lifelong learning.
期刊最新文献
Retinopathy in Mucopolysaccharidoses. Associations between School-Based Vision Program Outcomes and School Characteristics in 410 Schools. Risk of uveitis among E-Cigarette Users: a multi-institutional TriNetX study. Re: Lin et al.: Dexamethasone intracanalicular insert for clinically significant aqueous-deficient dry eye: a randomized controlled trial. (Ophthalmology. 2024;131:1033-1044). Reply.
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