Low Preoperative Albumin Levels Significantly Associated with Increased Risk of Wound Infection and Bleeding After Panniculectomy.

IF 0.7 4区 医学 Q4 SURGERY Plastic surgery Pub Date : 2024-10-25 DOI:10.1177/22925503241292350
Fiona S Griffin, Thor S Stead, Victoria G Zeyl, Raman Mehrzad, Victor A King, Loree K Kalliainen
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Abstract

Introduction: Panniculectomy is recognized to have a high complication rate with up to 56% of patients having postoperative wound healing problems. As they are generally elective procedures, surgeons have the chance to optimize preoperative variables. We reviewed the relationship between preoperative serum albumin and BMI with short-term postoperative panniculectomy complications. Methods: Patients undergoing panniculectomy between January 2005 and December 2019 were identified via CPT code 15830 from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP). Multivariate logistic regression was performed on intra/postoperative bleeding and postoperative wound infection against preoperative serum albumin, diabetes status, age, body mass index (BMI), and smoking status. Odds ratios were adjusted for comorbidities. We established statistical significance at p value <0.01. Results: Out of 1472 patients, 69 sustained intra/postoperative bleeding and 31 suffered wound infection. Lower preoperative albumin levels (R2 = 16.3%, p < 0.0001) and elevated BMI (R2 = 9.4%, p < 0.0001) were both significantly associated with increased likelihood of wound infection. For every 1 g/dL decrease in albumin, patients' odds of bleeding increased 1.85 (OR = 1.85, CI 95%= [1.14-2.99]) times, and odds of wound infection increased 5.03 (OR = 5.03, CI 95%= [2.78-9.10]) times (p < 0.0001). BMI and albumin were weakly correlated (r = -0.28) suggesting each had independent effects on complications. Conclusion: In patients undergoing panniculectomy, preoperative albumin level is significantly inversely associated with postoperative bleeding and wound complications. More research is needed to evaluate whether proactively optimizing albumin may reduce complications.

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术前白蛋白水平低与卵巢环切除术后伤口感染和出血风险增加有显著关系
介绍:卵巢环切除术的并发症发生率很高,高达 56% 的患者术后会出现伤口愈合问题。由于这些手术通常是选择性手术,因此外科医生有机会优化术前变量。我们研究了术前血清白蛋白和体重指数与胰腺切除术术后短期并发症之间的关系。方法通过美国外科学院国家外科质量改进计划(ACS-NSQIP)中的 CPT 代码 15830,对 2005 年 1 月至 2019 年 12 月间接受卵巢环切除术的患者进行识别。针对术前血清白蛋白、糖尿病状况、年龄、体重指数(BMI)和吸烟状况,对术中/术后出血和术后伤口感染进行了多变量逻辑回归。比值比已根据合并症进行调整。我们以 p 值确定统计显著性:在 1472 例患者中,69 例患者术中/术后出血,31 例患者伤口感染。术前白蛋白水平较低(R2 = 16.3%,P 结论:术前白蛋白水平较低可能导致术后出血:在接受泛影葡胺切除术的患者中,术前白蛋白水平与术后出血和伤口并发症明显成反比。需要更多研究来评估主动优化白蛋白是否能减少并发症。
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来源期刊
Plastic surgery
Plastic surgery Medicine-Surgery
CiteScore
1.70
自引率
0.00%
发文量
73
期刊介绍: Plastic Surgery (Chirurgie Plastique) is the official journal of the Canadian Society of Plastic Surgeons, the Canadian Society for Aesthetic Plastic Surgery, Group for the Advancement of Microsurgery, and the Canadian Society for Surgery of the Hand. It serves as a major venue for Canadian research, society guidelines, and continuing medical education.
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