INTRAUTERINE TOXIC METALS EXPOSURE AND NEXT GENERATIONAL EFFECTS ON NEONATAL ANTHROPOMETRIC DETERMINANTS IN ABAKALIKI, SOUTH EAST NIGERIA.

Q4 Medicine West African journal of medicine Pub Date : 2024-11-10

C E Eze, C Frazzoli, O E Orisakwe

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Abstract

Introduction: Growth restriction has been associated with the risk of none communicable disease. Many anthropometric determinants like birth weight, birth length, and pondoral Index, are related to maternal suboptimal nutrition and infants' deficiency of some essential heavy metals.

Objective: The specific objective of this study is to determine the extent of toxic metals in the cord blood, birth outcomes, and their effect on the biophysical profiles of neonates.

Methods: The cord blood of 30 preterm, 30 term newborns, and 60 maternal veinous blood were analysed using an Atomic Absorption Spectrometer (Analyst 200 Perkin-Elmer, USA). Metals such as aluminum, antimony, arsenic, cadmium, lead, and mercury were determined by measuring the levels of these metals in cord blood and maternal blood respectively.

Results: Findings thus suggest that preterms are particularly susceptible to toxicity on somatic parameters.

Conclusions: Therefore, safety measures should be taken to prevent human contamination and exposure during pregnancy.

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在尼日利亚东南部的阿巴卡利基，宫内有毒金属暴露和对新生儿人体测量决定因素的下一代影响。

介绍：生长受限与非传染性疾病的风险有关。许多人体测量决定因素，如出生体重、出生身长和池塘指数，都与母体营养不足和婴儿缺乏某些必需的重金属有关：本研究的具体目标是确定脐带血中有毒金属的含量、出生结果及其对新生儿生物物理特征的影响：方法：使用原子吸收光谱仪（Analyst 200 Perkin-Elmer，美国）对 30 名早产儿、30 名足月新生儿的脐带血和 60 名产妇的静脉血进行分析。通过测量脐带血和母体血液中铝、锑、砷、镉、铅和汞等金属的含量，分别确定了这些金属的含量：结果：研究结果表明，早产儿特别容易受到躯体参数毒性的影响：因此，应采取安全措施，防止人类在妊娠期间受到污染和接触。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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West African journal of medicine Medicine-Medicine (all)

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