J L Barcia-Salorio, V Vanaclocha, M Cerdá, J Ciudad, L López-Gómez
{"title":"Response of experimental epileptic focus to focal ionizing radiation.","authors":"J L Barcia-Salorio, V Vanaclocha, M Cerdá, J Ciudad, L López-Gómez","doi":"10.1159/000100740","DOIUrl":null,"url":null,"abstract":"<p><p>An experimental model of cobalt-induced epilepsy was performed on 15 cats. 3 months later, they were irradiated by means of a gamma source with a total target dose of 10 Gy. One month after irradiation all EEG recordings returned to normal, while a control group maintained the epileptiform traces. Histological study of the irradiated foci showed neuronal reafferentation. The action mechanism of ionizing radiation over epileptogenic foci in relation to this reafferentation and neuronal plasticity mechanisms is discussed.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"50 1-6","pages":"359-64"},"PeriodicalIF":0.0000,"publicationDate":"1987-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000100740","citationCount":"24","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied neurophysiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000100740","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 24
Abstract
An experimental model of cobalt-induced epilepsy was performed on 15 cats. 3 months later, they were irradiated by means of a gamma source with a total target dose of 10 Gy. One month after irradiation all EEG recordings returned to normal, while a control group maintained the epileptiform traces. Histological study of the irradiated foci showed neuronal reafferentation. The action mechanism of ionizing radiation over epileptogenic foci in relation to this reafferentation and neuronal plasticity mechanisms is discussed.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
