The role of the United Kingdom national poisons information service (NPIS) in the diagnosis of death according to neurological criteria in poisoned and non-poisoned patients.

IF 2.1 Q3 CRITICAL CARE MEDICINE Journal of the Intensive Care Society Pub Date : 2024-10-09 DOI:10.1177/17511437241289000
Jeanie Worthington, Leon Cohen, Ian Thomas, Laurence Gray, Euan Sandilands, Emma Moyns
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Abstract

The diagnosis of death by neurological criteria (DNC) requires the exclusion of any clinical effect attributable to xenobiotics. We undertook a retrospective analysis of enquiries to the National Poisons Information Service (NPIS) relating to DNC over a 10-year period. Enquiries were categorised as toxicological, where exposure to a non-therapeutically administered xenobiotic was implicated in the clinical presentation and non-toxicological where exposure to the xenobiotic was not the primary cause of the clinical state. The frequency of enquiry to the NPIS regarding xenobiotics and DNC demonstrates that it remains a valuable source of expert advice.

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英国国家毒物信息服务机构(NPIS)在根据神经学标准诊断中毒和非中毒患者死亡中的作用。
诊断神经性死亡(DNC)需要排除任何可归因于异生物体的临床效应。我们对国家毒物信息服务机构(NPIS)10年来与DNC有关的查询进行了回顾性分析。如果临床表现与暴露于非治疗用的异生物体有关,则查询被归类为毒理学查询;如果暴露于异生物体不是临床症状的主要原因,则查询被归类为非毒理学查询。向 NPIS 查询有关异生物体和 DNC 的频率表明,它仍然是专家建议的重要来源。
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来源期刊
Journal of the Intensive Care Society
Journal of the Intensive Care Society Nursing-Critical Care Nursing
CiteScore
4.40
自引率
0.00%
发文量
45
期刊介绍: The Journal of the Intensive Care Society (JICS) is an international, peer-reviewed journal that strives to disseminate clinically and scientifically relevant peer-reviewed research, evaluation, experience and opinion to all staff working in the field of intensive care medicine. Our aim is to inform clinicians on the provision of best practice and provide direction for innovative scientific research in what is one of the broadest and most multi-disciplinary healthcare specialties. While original articles and systematic reviews lie at the heart of the Journal, we also value and recognise the need for opinion articles, case reports and correspondence to guide clinically and scientifically important areas in which conclusive evidence is lacking. The style of the Journal is based on its founding mission statement to ‘instruct, inform and entertain by encompassing the best aspects of both tabloid and broadsheet''.
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