Effect of ultrasound-guided internal branch of superior laryngeal nerve block on postoperative sore throat induced by a NIM-EMG-ETT: study protocol for a double-blinded randomized controlled trial.

IF 2 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Trials Pub Date : 2024-11-08 DOI:10.1186/s13063-024-08591-y

Xi Liu, Aizhong Wang, Zhihua Jiao, Jun Yao, Xiaoxiao Chen, Limin Luo, Hui Zhang

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Abstract

Background: Postoperative sore throat (POST) is a common complaint after general anaesthesia. The prevalence of POST caused by a neural integrity monitor electromyography endotracheal tube (NIM-EMG-ETT) is high. This study aimed to determine whether ultrasound-guided internal branch of superior laryngeal nerve block (iSLNB) could alleviate POST associated with a NIM-EMG-ETT.

Methods: This randomized controlled trial plans to enroll 182 patients scheduled to undergo general anaesthesia with a NIM-EMG-ETT. Patients will be randomly allocated into the iSLNB group or the control group according to randomized numbers generated by Excel. After induction, patients in the iSLNB group will undergo ultrasound-guided iSLNB with ropivacaine, and patients in the control group will undergo the same procedure with normal saline. The prevalence, severity, visual analogue scale score of POST, and postoperative acoustic analysis will be recorded.

Discussion: To the best of our knowledge, this is the first study to evaluate the effect of ultrasound-guided iSLNB with ropivacaine on the mitigation of POST induced by NIM-EMG-ETT. Our study will provide clinical answers to alleviate POST induced by NIM-EMG-ETT. The results of this study may provide a safe method to prevent POST caused by NIM-EMG-ETT.

Trial registration: Chinese Clinical Trial Registry, ChiCTR2300076393. Registered on October 24, 2023, http://www.chictr.org.cn/index.aspx .

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超声引导下喉上神经内支阻滞对 NIM-EMG-ETT 引起的术后咽喉痛的影响：双盲随机对照试验的研究方案。

背景：术后咽喉痛（POST）是全身麻醉后的常见症状。由神经完整性监测肌电图气管插管（NIM-EMG-ETT）引起的术后咽喉痛发病率很高。本研究旨在确定超声引导下的喉上神经内支阻滞（iSLNB）能否减轻与NIM-EMG-ETT相关的POST：这项随机对照试验计划招募 182 名计划接受 NIM-EMG-ETT 全身麻醉的患者。患者将根据 Excel 生成的随机数字被随机分配到 iSLNB 组或对照组。诱导后，iSLNB 组患者将在超声引导下使用罗哌卡因进行 iSLNB，对照组患者将使用生理盐水进行同样的手术。将记录POST的发生率、严重程度、视觉模拟量表评分以及术后声学分析：据我们所知，这是第一项评估在超声引导下使用罗哌卡因进行 iSLNB 对减轻 NIM-EMG-ETT 诱发的 POST 的影响的研究。我们的研究将为缓解 NIM-EMG-ETT 诱发的 POST 提供临床答案。本研究的结果可能会为预防 NIM-EMG-ETT 引起的 POST 提供一种安全的方法：试验注册：中国临床试验注册中心，ChiCTR2300076393。注册日期：2023年10月24日，http://www.chictr.org.cn/index.aspx 。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trials 医学-医学：研究与实验

CiteScore

3.80

自引率

4.00%

发文量

966

审稿时长

6 months

期刊介绍： Trials is an open access, peer-reviewed, online journal that will encompass all aspects of the performance and findings of randomized controlled trials. Trials will experiment with, and then refine, innovative approaches to improving communication about trials. We are keen to move beyond publishing traditional trial results articles (although these will be included). We believe this represents an exciting opportunity to advance the science and reporting of trials. Prior to 2006, Trials was published as Current Controlled Trials in Cardiovascular Medicine (CCTCVM). All published CCTCVM articles are available via the Trials website and citations to CCTCVM article URLs will continue to be supported.