Evelin Tiralongo, Vanessa Vigar, Keith Potent, Robert S Ware
{"title":"Does a Polyherbal Medicine Enhance Cognition in Healthy Older Adults? An Exploratory Open-Label Study.","authors":"Evelin Tiralongo, Vanessa Vigar, Keith Potent, Robert S Ware","doi":"10.1089/jicm.2023.0620","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Objective:</i></b> This 12-week open-label study evaluated a multi-herbal tablet containing <i>Reynoutria japonica</i>, <i>Vitis vinifera</i>, <i>Silybum marianum</i>, <i>Ginkgo biloba</i>, and <i>Panax ginseng</i>, for potential improvement of cognitive function in 25 healthy older adults (50-75 years). <b><i>Methods:</i></b> The primary outcome, cognition, was assessed using the Cambridge Neuropsychological Test Automated Battery. <b><i>Results:</i></b> Significant improvement in working memory was observed. Errors in the Paired Associate Learning (PAL) task and spatial working memory reduced by -7.9 (95%CI: -12.3, -3.5) and -3.3 (95%CI: -6.3, -0.3) respectively, while PAL memory score increased by 2.0 (95%CI: 0.9, 3.1). <i><b>Conclusion:</b></i> These preliminary results suggest memory improvement, but further rigorous testing is needed.</p>","PeriodicalId":29734,"journal":{"name":"Journal of Integrative and Complementary Medicine","volume":" ","pages":"209-213"},"PeriodicalIF":1.3000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Integrative and Complementary Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1089/jicm.2023.0620","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/10/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This 12-week open-label study evaluated a multi-herbal tablet containing Reynoutria japonica, Vitis vinifera, Silybum marianum, Ginkgo biloba, and Panax ginseng, for potential improvement of cognitive function in 25 healthy older adults (50-75 years). Methods: The primary outcome, cognition, was assessed using the Cambridge Neuropsychological Test Automated Battery. Results: Significant improvement in working memory was observed. Errors in the Paired Associate Learning (PAL) task and spatial working memory reduced by -7.9 (95%CI: -12.3, -3.5) and -3.3 (95%CI: -6.3, -0.3) respectively, while PAL memory score increased by 2.0 (95%CI: 0.9, 3.1). Conclusion: These preliminary results suggest memory improvement, but further rigorous testing is needed.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
