Renata Fogaça Borges, Vanessa Krebs Genro, Carlos Augusto Bastos de Souza, Tatiana Ferreira Michelon, Isabel Meneghetti Coimbra, João Sabino Lahorgue da Cunha-Filho
{"title":"Increased antinuclear (anti-Sm) antibodies in infertile patients with peritoneal endometriosis.","authors":"Renata Fogaça Borges, Vanessa Krebs Genro, Carlos Augusto Bastos de Souza, Tatiana Ferreira Michelon, Isabel Meneghetti Coimbra, João Sabino Lahorgue da Cunha-Filho","doi":"10.5935/1518-0557.20240070","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to evaluate the intensity of five antibodies against extractable nuclear antigens (ENA: RNP, ScL-70, SS-B, SS-A, and Sm) in infertile patients with endometriosis.</p><p><strong>Methods: </strong>We investigated infertile women with minimal/mild endometriosis (n=43) and fertile women (n=46).</p><p><strong>Results: </strong>The intensity of immunoreactions was also similar for anti-RNP and anti-SS-A antibodies. However, the intensity of immunoreactivity for anti-Sm antibodies was higher in the endometriosis group.</p><p><strong>Conclusions: </strong>Patients with minimal/mild endometriosis have higher levels of anti-Sm autoantibodies.</p>","PeriodicalId":46364,"journal":{"name":"Jornal Brasileiro de Reproducao Assistida","volume":" ","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jornal Brasileiro de Reproducao Assistida","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5935/1518-0557.20240070","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The aim of this study is to evaluate the intensity of five antibodies against extractable nuclear antigens (ENA: RNP, ScL-70, SS-B, SS-A, and Sm) in infertile patients with endometriosis.
Methods: We investigated infertile women with minimal/mild endometriosis (n=43) and fertile women (n=46).
Results: The intensity of immunoreactions was also similar for anti-RNP and anti-SS-A antibodies. However, the intensity of immunoreactivity for anti-Sm antibodies was higher in the endometriosis group.
Conclusions: Patients with minimal/mild endometriosis have higher levels of anti-Sm autoantibodies.