Biomechanical analysis of nickel-titanium (NiTi)-cobalt-chromium (CoCr) hybrid-braided dense-mesh stents for carotid artery stenosis.

IF 1.7 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Computer Methods in Biomechanics and Biomedical Engineering Pub Date : 2024-11-14 DOI:10.1080/10255842.2024.2428720
Yunchuan Zhao, Haipo Cui, Xudong Guo, Jingcheng Lang
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Abstract

This study investigates NiTi-CoCr hybrid carotid artery stents to enhance mechanical properties over NiTi-only designs. Different configurations (24NiTi, 20NiTi-4CoCr, 16NiTi-8CoCr, and 12NiTi-12CoCr) were evaluated through radial compression and bending simulations. The 12NiTi-12CoCr stent showed the highest radial support (39.37 N) and increased bending strength by 77.96%. When modeled in a stenotic artery, this stent reduced stenosis from 81.52% to 29.33% and improved blood flow dynamics, alleviating high-pressure zones and balancing wall shear stress. These results suggest that CoCr wires improve stent performance, with the 12NiTi-12CoCr stent offering significant biomechanical and hemodynamic benefits.

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镍钛(NiTi)-钴铬(CoCr)混合编织致密网支架治疗颈动脉狭窄的生物力学分析。
本研究探讨了镍钛钴混合颈动脉支架,以提高其机械性能。通过径向压缩和弯曲模拟,对不同配置(24镍钛、20镍钛-4钴铬、16镍钛-8钴铬、12镍钛-12钴铬)进行了评估。12NiTi-12CoCr 支架的径向支撑力最大(39.37 N),弯曲强度增加了 77.96%。在狭窄动脉中建模时,这种支架将狭窄程度从 81.52% 降低到 29.33%,并改善了血流动力学,减轻了高压区,平衡了管壁剪切应力。这些结果表明,钴铬合金丝可改善支架性能,其中 12NiTi-12CoCr 支架在生物力学和血液动力学方面具有显著优势。
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来源期刊
CiteScore
4.10
自引率
6.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍: The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.
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