Good vibes for the brain - Placebo versus real vibration in patients with chronic neck pain: A randomized cross-over study

IF 2.2 3区医学 Q1 REHABILITATION Musculoskeletal Science and Practice Pub Date : 2024-11-01 DOI:10.1016/j.msksp.2024.103210

Sandra Preiss , Wolfgang Taube , Sandra Helmstädter , Larissa Bentz , Konstantin Beinert

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Abstract

Background

Neck muscle vibration decreases pain and improves sensorimotor impairments in patients with chronic neck pain. However, the impact of placebo on these effects are still unclear.

Objective

The aim was to evaluate the effect of neck muscle vibration compared to placebo neck muscle vibration in patients with chronic neck pain.

Methods

Twenty-three people with chronic neck pain participated in this double-blinded, randomized crossover study. After baseline assessment at day 1, patients received either neck muscle vibration or placebo neck muscle vibration at day 2. At day 3, patients underwent the other treatment. The primary outcomes assessed at each day were active cervical joint position sense acuity, resting pain, and pressure pain threshold.

Results

Cervical joint position sense revealed a significant time effect (F1, 22 = 4.366, p = 0.016, η2 = 0.902). Post-hoc testing revealed significant increases in cervical joint position sense after neck muscle vibration (p = 0.023; d = 0.602) but not after placebo vibration. Resting pain (F1, 22 = 7.550, p = 0.003, η2 = 0.418) displayed significant time effects for neck muscle vibration and placebo vibration. Pressure pain threshold demonstrated a significant time to condition effect (F1, 22 = 6.146; p = 0.008, η2 = 0.369). Post-hoc tests revealed that only neck muscle vibration significantly increased pressure pain threshold (p = 0.043, d = 0.516).

Conclusion

The study demonstrates the efficacy of neck muscle vibration to decrease neck pain and improve cervical joint position sense in patients with chronic neck pain. Nevertheless, the influence of placebo effects should not be underestimated as they may contribute to these effects, indicated by similar decreases in resting pain.

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对大脑有益的振动--慢性颈痛患者服用安慰剂与实际振动的对比：随机交叉研究。

背景：颈部肌肉振动可减轻慢性颈痛患者的疼痛并改善其感觉运动障碍。然而，安慰剂对这些效果的影响仍不清楚：目的：评估颈部肌肉振动与安慰剂颈部肌肉振动对慢性颈痛患者的影响：23名慢性颈部疼痛患者参加了这项双盲随机交叉研究。在第 1 天进行基线评估后，患者在第 2 天接受颈部肌肉振动或安慰剂颈部肌肉振动。第 3 天，患者接受另一种治疗。每天评估的主要结果是活动颈椎关节位置感敏锐度、静息痛和压痛阈值：结果：颈椎关节位置感显示出显著的时间效应（F1，22 = 4.366，P = 0.016，η2 = 0.902）。事后检验显示，颈部肌肉振动后颈椎关节位置感明显增强（p = 0.023; d = 0.602），而安慰剂振动后则没有。静息痛（F1，22 = 7.550，p = 0.003，η2 = 0.418）对颈部肌肉振动和安慰剂振动有显著的时间效应。压痛阈值显示出显著的时间条件效应（F1，22 = 6.146；p = 0.008，η2 = 0.369）。事后检验显示，只有颈部肌肉振动能显著提高压痛阈值（p = 0.043，d = 0.516）：研究表明，颈部肌肉振动对减轻慢性颈痛患者的颈部疼痛和改善颈椎关节位置感有一定疗效。尽管如此，安慰剂效应的影响也不容低估，因为安慰剂效应可能会促进这些效果的产生，静息疼痛的类似减轻就说明了这一点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Musculoskeletal Science and Practice Health Professions-Physical Therapy, Sports Therapy and Rehabilitation

CiteScore

4.10

自引率

8.70%

发文量

152

审稿时长

48 days

期刊介绍： Musculoskeletal Science & Practice, international journal of musculoskeletal physiotherapy, is a peer-reviewed international journal (previously Manual Therapy), publishing high quality original research, review and Masterclass articles that contribute to improving the clinical understanding of appropriate care processes for musculoskeletal disorders. The journal publishes articles that influence or add to the body of evidence on diagnostic and therapeutic processes, patient centered care, guidelines for musculoskeletal therapeutics and theoretical models that support developments in assessment, diagnosis, clinical reasoning and interventions.