Morus alba: natural and valuable effects in weight loss management.

Frontiers in clinical diabetes and healthcare Pub Date : 2024-10-25 eCollection Date: 2024-01-01 DOI:10.3389/fcdhc.2024.1395688
Foteini Ntalouka, Athina Tsirivakou
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Abstract

Overweight and obesity are conditions associated with serious comorbidities, such as diabetes and cardiovascular disease. Prevalence of excessive fat accumulation is increasing worldwide, and thus the need for efficient and sustainable weight loss regimes has become a major issue in clinical practice. Despite the important advances in the development of anti-obesity medications (AOM), their side effects, cost, and accessibility, are limiting factors for their routine use. Conversely, the studies of medicinal plants for weight management holds strong promise as a growing area of research. This review consolidates the representative evidence about the beneficial impacts of Morus alba on weight management and associated metabolic parameters, encompassing: inhibition of digestive enzymes, and thus contribution to the energy deficit required for weight loss, improvements in glucose and lipid metabolism, and attenuation of adiposity. Findings from in vitro, in vivo, and clinical investigations reviewed in the paper, demonstrate that white mulberry extracts have the potency to supplement efficiently and safely a healthy weight management approach.

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Morus alba:在减肥管理方面的天然和宝贵功效。
超重和肥胖与糖尿病和心血管疾病等严重并发症有关。在全球范围内,脂肪过度堆积的发病率正在不断上升,因此对高效、可持续的减肥方法的需求已成为临床实践中的一个重要问题。尽管在开发抗肥胖药物(AOM)方面取得了重大进展,但其副作用、成本和可及性是限制其常规使用的因素。相反,药用植物在体重管理方面的研究则大有可为,是一个不断发展的研究领域。本综述整合了有关桑白皮对体重管理和相关代谢参数有益影响的代表性证据,包括:抑制消化酶,从而有助于减轻体重所需的能量不足;改善葡萄糖和脂质代谢;减少脂肪。本文回顾的体外、体内和临床研究结果表明,白桑椹提取物具有高效、安全地补充健康体重管理方法的功效。
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