Joseph G. Gall (1928-2024): Cell biologist, naturalist, and mentor extraordinaire.

IF 7.4 1区 生物学 Q1 CELL BIOLOGY Journal of Cell Biology Pub Date : 2024-12-02 Epub Date: 2024-11-15 DOI:10.1083/jcb.202410071
Susan A Gerbi, Virginia A Zakian, Elizabeth H Blackburn
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Abstract

Joseph Grafton Gall (1928-2024), a founder of modern cell biology, made foundational discoveries on eukaryotic chromosomes and RNA biogenesis. His major contributions include the development of in situ hybridization (later called FISH), demonstration of one DNA double helix/chromosome, isolation of the first eukaryote gene, localization of satellite DNA to centromeric heterochromatin, determination of the first telomeric DNA sequence, and elucidating the structure and functions of Cajal bodies. He was an expert microscopist, a scholar of science history, and an avid naturalist. These attributes, together with his ready embrace of new technologies, contributed to his remarkable success. He was also an early and strong supporter of women in science. His contributions to science and mentoring were recognized by numerous awards including the American Society for Cell Biology's E.B. Wilson Medal, the Society for Developmental Biology's Lifetime Achievement Award, the Albert Lasker Special Achievement Award in Medical Research, and the AAAS Mentor Award for Lifetime Achievement.

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约瑟夫-加尔(Joseph G. Gall,1928-2024 年):细胞生物学家、博物学家和杰出导师。
约瑟夫-格拉夫顿-加尔(Joseph Grafton Gall,1928-2024 年)是现代细胞生物学的奠基人,在真核染色体和 RNA 生物发生方面取得了奠基性发现。他的主要贡献包括发展了原位杂交(后来称为 FISH),证明了一个 DNA 双螺旋/染色体,分离了第一个真核基因,将卫星 DNA 定位到中心异染色质,确定了第一个端粒 DNA 序列,以及阐明了 Cajal 体的结构和功能。他是显微镜专家、科学史学者和狂热的博物学家。这些特质加上他对新技术的乐于接受,成就了他的非凡成就。他还是科学界女性的早期坚定支持者。他对科学和指导工作的贡献得到了众多奖项的认可,其中包括美国细胞生物学学会的 E.B. 威尔逊奖章、发育生物学学会的终身成就奖、阿尔伯特-拉斯克医学研究特别成就奖以及美国科学院终身成就导师奖。
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来源期刊
Journal of Cell Biology
Journal of Cell Biology 生物-细胞生物学
CiteScore
12.60
自引率
2.60%
发文量
213
审稿时长
1 months
期刊介绍: The Journal of Cell Biology (JCB) is a comprehensive journal dedicated to publishing original discoveries across all realms of cell biology. We invite papers presenting novel cellular or molecular advancements in various domains of basic cell biology, along with applied cell biology research in diverse systems such as immunology, neurobiology, metabolism, virology, developmental biology, and plant biology. We enthusiastically welcome submissions showcasing significant findings of interest to cell biologists, irrespective of the experimental approach.
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