{"title":"Targeting TUBB3 Suppresses Anoikis Resistance and Bone Metastasis in Prostate Cancer (Adv. Healthcare Mater. 28/2024)","authors":"Bingqi Dong, Yanlun Gu, Xiaojiao Sun, Xin Wang, Ying Zhou, Zhuona Rong, Jixin Zhang, Xuedong Shi, Zhuo Zhang, Xu He, Lin Chen, Qingqing Xiong, Xiaocong Pang, Yimin Cui","doi":"10.1002/adhm.202470181","DOIUrl":null,"url":null,"abstract":"<p><b>Prostate Cancer Bone Metastasis</b></p><p>In article 2400673, Qingqing Xiong, Xiaocong Pang, Yimin Cui, and co-workers identify TUBB3 as a key anoikis-related prognostic gene correlated with prostate cancer bone metastasis. The dandelion with drifting seeds symbolizes the anoikis-resistant tumor that can easily metastasize to bone tissue. The gardener holds bone-targeting lipid nanoparticles encapsulating siRNA targeting TUBB3 to attenuate the progression of prostate cancer bone metastasis.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":"13 28","pages":""},"PeriodicalIF":10.0000,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202470181","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Healthcare Materials","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adhm.202470181","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Prostate Cancer Bone Metastasis
In article 2400673, Qingqing Xiong, Xiaocong Pang, Yimin Cui, and co-workers identify TUBB3 as a key anoikis-related prognostic gene correlated with prostate cancer bone metastasis. The dandelion with drifting seeds symbolizes the anoikis-resistant tumor that can easily metastasize to bone tissue. The gardener holds bone-targeting lipid nanoparticles encapsulating siRNA targeting TUBB3 to attenuate the progression of prostate cancer bone metastasis.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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