Spray Drying Microencapsulation of Antioxidant Bioflavonoids: A Bibliometric Analysis and Review on Recent Research Landscape (2013–2023) and Process Optimization

Abstract

Spray drying has become a prevalent method for microencapsulating antioxidant bioflavonoids, offering cost-effectiveness and suitability for commercial nutraceutical production. Yet, challenges persist due to powder instability stemming from material compatibility issues and suboptimal operating conditions. A bibliometric analysis spanning 2013–2023 explored this research domain, revealing a burgeoning interest globally, notably from China, India, and Brazil. Keyword analysis highlighted prevalent themes like response surface methodology and process optimization, emphasizing maltodextrin's frequent use in encapsulation. Research delved into critical parameters such as wall material selection, compound-to-wall ratio, and operational optimization encompassing flow rate and inlet temperature. These insights drive advancements in spray drying technology, enabling the production of premium-quality nutraceutical ingredients while addressing stability concerns. This research underscores the significance of optimizing spray drying processes to enhance the efficacy and shelf life of bioflavonoid-based nutraceuticals for commercial viability.