Hyejun Park, Seunghwan Shim, Hayoung Jeon, Hwayoung Lee, Kiho Lee, Kyeong Lee, Jae Kyun Lee, Hitesh B. Jalani, Yongseok Choi
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引用次数: 0
Abstract
Herein, we have developed palladium-trifluoroacetate-catalyzed carbo-palladation reaction of pyrrole-2-carbonitriles and aryl boronic acids leading to functionally diverse pyrrolo[1,2-α]pyrazines under thoroughly optimized reaction conditions. The reaction proceeded smoothly and allowed the diversity-oriented synthesis of pyrrolo[1,2-α]pyrazines with broad substrate scope with respect to pyrrole-2-carbonitriles and aryl boronic acids.
期刊介绍:
The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.