[Use of sacituzumab govitecan in frail patients with skin disease.]

Q3 Medicine Recenti progressi in medicina Pub Date : 2024-11-01 DOI:10.1701/4365.43615
Eugenia Arrivas Bajardi
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Abstract

The clinical case described concerns a 53-year-old patient with triple-negative disease, metastatic to the skin, fragile, not due to comorbidities, but due to toxicities from previous antiblastic treatments. The major toxicities reported, even previously, were inherent to bone marrow function, with prolonged neutropenia, despite the use of granulocyte growth factor (GCSF). The patient has no family history of breast cancer and does not have a mutation in the BRCA1/2 genes. In pathological history, only arterial hypertension under medical therapy with nebivolol.

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[在患有皮肤病的体弱患者中使用萨希珠单抗戈维替康]。
本临床病例涉及一名 53 岁的三阴性患者,该患者的皮肤已发生转移,不是因为合并症,而是因为之前的抗肿瘤治疗产生了毒性。即使是以前报告的主要毒性也是骨髓功能固有的,尽管使用了粒细胞生长因子(GCSF),但仍出现了长期的中性粒细胞减少症。患者没有乳腺癌家族史,也没有 BRCA1/2 基因突变。病史中只有动脉高血压,正在接受奈必洛尔(nebivolol)药物治疗。
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来源期刊
Recenti progressi in medicina
Recenti progressi in medicina Medicine-Medicine (all)
CiteScore
0.90
自引率
0.00%
发文量
143
期刊介绍: Giunta ormai al sessantesimo anno, Recenti Progressi in Medicina continua a costituire un sicuro punto di riferimento ed uno strumento di lavoro fondamentale per l"ampliamento dell"orizzonte culturale del medico italiano. Recenti Progressi in Medicina è una rivista di medicina interna. Ciò significa il recupero di un"ottica globale e integrata, idonea ad evitare sia i particolarismi della informazione specialistica sia la frammentazione di quella generalista.
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